Literature DB >> 9168970

Genetic and physical delineation of the region of the mouse deafness mutation shaker-2.

Y Wakabayashi1, Y Kikkawa, Y Matsumoto, T Shinbo, S Kosugi, D Chou, M Furuya, K Jishage, T Noda, H Yonekawa, R Kominami.   

Abstract

A total of 951 backcross progeny have been obtained from a backcross segregating for the mouse deafness mutation, shaker-2(sh-2). Linkage analysis provides a detailed genetic map in the vicinity of sh-2 which comprises 40 backcross mice identified as recombinant within a 4 cM region. This allows construction of a contig consisting of 21 BAC clones across an approximately 700-kb region of sh-2. This covers the entire nonrecombinant region of sh-2 and is therefore useful to facilitate the identification of genes in the sh-2 region.

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Year:  1997        PMID： 9168970     DOI： 10.1006/bbrc.1997.6595

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  2 in total

1.  Myosin XVA expression in the pituitary and in other neuroendocrine tissues and tumors.

Authors:  R V Lloyd; S Vidal; L Jin; S Zhang; K Kovacs; E Horvath; B W Scheithauer; E T Boger; R A Fridell; T B Friedman
Journal:  Am J Pathol       Date:  2001-10       Impact factor: 4.307

2.  Genetic mapping refines DFNB3 to 17p11.2, suggests multiple alleles of DFNB3, and supports homology to the mouse model shaker-2.

Authors:  Y Liang; A Wang; F J Probst; I N Arhya; T D Barber; K S Chen; D Deshmukh; D F Dolan; J T Hinnant; L E Carter; P K Jain; A K Lalwani; X C Li; J R Lupski; S Moeljopawiro; R Morell; C Negrini; E R Wilcox; S Winata; S A Camper; T B Friedman
Journal:  Am J Hum Genet       Date:  1998-04       Impact factor: 11.025
  2 in total

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