| Literature DB >> 9168203 |
J Q Zheng1, M M Poo, J A Connor.
Abstract
Cultured Xenopus spinal neurons exhibit chemotropic turning toward the source of neurotransmitters acetylcholine and glutamate. Here we review the experimental evidence that transmitter-induced turning of the growth cone is mediated by an influx of Ca2+, that a gradient of intracellular Ca2+ within the growth cone is responsible for the directional growth cone response, and that asymmetric filopodia formation precedes and is essential for the turning response.Entities:
Mesh：
Substances：
Year: 1996 PMID： 9168203
Source DB: PubMed Journal: Perspect Dev Neurobiol ISSN： 1026-7697