Thrombosis of the proximal greater saphenous vein: ultrasonographic diagnosis and clinical significance.

Eleven of 985 (1.1%) patients referred for leg ultrasonographic examinations to evaluate for deep venous thrombosis over a 3 year period were found to have isolated proximal greater saphenous vein thrombosis. Retrospective review of their treatments and sequelae showed that six patients (55%) initially treated with anticoagulant medication or high vein ligation had no further sequelae. Of four patients (36%) not initially treated, two subsequently developed pulmonary embolus, one had clot propagation into the common femoral vein, and one developed noncontiguous deep venous thrombosis. The findings of this review would suggest aggressive treatment for isolated upper greater saphenous vein thrombosis.