| Literature DB >> 9163557 |
H Yamamoto1, T Saito, Y Kaneko, D Kersey, V W Yong, E G Bremer, E Mkrdichian, L Cerullo, J Leestma, J R Moskal.
Abstract
CMP-NeuAc: Galbeta1,3(4)GlcNAc alpha2,3-sialyltransferase (alpha2,3-ST) mRNA was expressed in human glioma specimens, human fetal astrocytes, and a panel of brain tumor cell lines. Maackia amurensis agglutinin staining revealed the presence of alpha2,3-linked sialic acids on glioma cell surfaces and extracellular matrices whereas normal human adult astrocytes were negative. Increased expression of alpha2,3-linked glycoprotein sialylation may play a role in glial tumorigenesis.Entities:
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Year: 1997 PMID： 9163557 DOI： 10.1016/s0006-8993(97)00241-2
Source DB: PubMed Journal: Brain Res ISSN： 0006-8993 Impact factor: 3.252