Literature DB >> 9163249

[An elevation in the level of autoantibodies to nerve-growth factor in the blood serum of schizophrenic children].

V M Bashina, I A Kozlova, T P Kliushnik, N V Simashkova, E V Danilovskaia, N L Gorbachevskaia, I L Turkova, L P Iakupova, V V Grachev.   

Abstract

The level of autoantibodies (AAB) to nerve growth factor (NGF) was examined in blood of mentally healthy children, children with early children schizophrenia as well as with Kanner's and Asperger's syndromes too. The elevated titer of AAB to NGF was determined in blood of children with acute, active state of disease; meanwhile the same titer wasn't changed in the state of stable remission or steady defective state as compared with control group. The correlation was found between the level of AAB to NGF and the degree of disease progression. The correlations which were revealed between AAB to NGF level and peculiarities of the clinical state of patients permitted to use this index as the objective marker of both the acuteness and the severity of the patient's state.

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Year:  1997        PMID: 9163249

Source DB:  PubMed          Journal:  Zh Nevrol Psikhiatr Im S S Korsakova        ISSN: 1997-7298


  5 in total

1.  Changes in the serum levels of autoantibody to nerve growth factor in patients with schizophrenia.

Authors:  T P Klyushnik; E V Danilovskaya; O E Vatolkina; I L Turkova; V A Orlova; V G Kaleda
Journal:  Neurosci Behav Physiol       Date:  1999 May-Jun

2.  Correlation between levels of autoantibodies to nerve growth factor and the clinical features of schizophrenia in children.

Authors:  T P Klyushnik; I L Turkova; E V Danilovskaya; I A Kozlova; V M Bashina; N V Simashkova; N K Babishchevich
Journal:  Neurosci Behav Physiol       Date:  2000 Mar-Apr

3.  Antibodies directed to Neisseria gonorrhoeae impair nerve growth factor-dependent neurite outgrowth in Rat PC12 cells.

Authors:  B Reuss
Journal:  J Mol Neurosci       Date:  2013-11-08       Impact factor: 3.444

4.  Autoantibodies to nerve growth factor in disorders of mental development in infants.

Authors:  T P Klyushnik; N S Sergienko; E V Danilovskaya; A V Goryunova; O I Maslova
Journal:  Neurosci Behav Physiol       Date:  2001 Mar-Apr

5.  HLA Immune Function Genes in Autism.

Authors:  Anthony R Torres; Jonna B Westover; Allen J Rosenspire
Journal:  Autism Res Treat       Date:  2012-02-15
  5 in total

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