Literature DB >> 9162475

Tumor suppressors: a developing role for p53?

P A Hall1, D P Lane.   

Abstract

An increasing body of evidence indicates that p53, the product of a tumour suppressor gene, has a role in development - could this developmental role have provided the primary driving force in the evolution of a protein best known as a stress-response integrator?

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Year:  1997        PMID： 9162475     DOI： 10.1016/s0960-9822(97)70074-5

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  17 in total

1.  Differential binding of NF1 transcription factor to P53 gene promoter and its depletion in human breast tumours.

Authors:  B K Nayak; B R Das
Journal:  Mol Biol Rep       Date:  1999-12       Impact factor: 2.316

2.  p53-inducible human homologue of Drosophila seven in absentia (Siah) inhibits cell growth: suppression by BAG-1.

Authors:  S Matsuzawa; S Takayama; B A Froesch; J M Zapata; J C Reed
Journal:  EMBO J       Date:  1998-05-15       Impact factor: 11.598

3.  Differences in p53 and Bcl-2 expression in relation to cell proliferation during the development of human embryos.

Authors:  V Lichnovský; Z Kolár; P Murray; A Hlobilková; D Cernochová; E Pospísilová; B Vojtĕsek; R Nenutil
Journal:  Mol Pathol       Date:  1998-06

4.  Differential effects on apoptosis induction in hepatocyte lines by stable expression of hepatitis B virus X protein.

Authors:  Nicola Fiedler; Ellen Quant; Ludger Fink; Jianguang Sun; Ralph Schuster; Wolfram H Gerlich; Stephan Schaefer
Journal:  World J Gastroenterol       Date:  2006-08-07       Impact factor: 5.742

5.  p53 Disruption Increases Uracil Accumulation in DNA of Murine Embryonic Fibroblasts and Leads to Folic Acid-Nonresponsive Neural Tube Defects in Mice.

Authors:  Erica R Lachenauer; Sally P Stabler; Martha S Field; Patrick J Stover
Journal:  J Nutr       Date:  2020-07-01       Impact factor: 4.798

6.  A direct intersection between p53 and transforming growth factor beta pathways targets chromatin modification and transcription repression of the alpha-fetoprotein gene.

Authors:  Deepti S Wilkinson; Stacey K Ogden; Sabrina A Stratton; Julie L Piechan; Thi T Nguyen; George A Smulian; Michelle Craig Barton
Journal:  Mol Cell Biol       Date:  2005-02       Impact factor: 4.272

7.  Mdm4 (Mdmx) regulates p53-induced growth arrest and neuronal cell death during early embryonic mouse development.

Authors:  Domenico Migliorini; Eros Lazzerini Denchi; Davide Danovi; Aart Jochemsen; Manuela Capillo; Alberto Gobbi; Kristian Helin; Pier Giuseppe Pelicci; Jean-Christophe Marine
Journal:  Mol Cell Biol       Date:  2002-08       Impact factor: 4.272

8.  p53 upregulation is a frequent response to deficiency of cell-essential genes.

Authors:  Nadia Danilova; Asako Kumagai; Jenny Lin
Journal:  PLoS One       Date:  2010-12-31       Impact factor: 3.240

9.  p53 functions as a negative regulator of osteoblastogenesis, osteoblast-dependent osteoclastogenesis, and bone remodeling.

Authors:  Xueying Wang; Hui-Yi Kua; Yuanyu Hu; Ke Guo; Qi Zeng; Qiang Wu; Huck-Hui Ng; Gerard Karsenty; Benoit de Crombrugghe; James Yeh; Baojie Li
Journal:  J Cell Biol       Date:  2005-12-27       Impact factor: 10.539

10.  Genetic studies of bone diseases: evidence for involvement of DNA damage response proteins in bone remodeling.

Authors:  Xueying Wang; Baojie Li
Journal:  Int J Biomed Sci       Date:  2007-12
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