Literature DB >> 9161009

Ni++ as a competitive inhibitor of calcium transport in mitochondria.

M Bragadin1, E R Viola.   

Abstract

The kinetics of Ca++ uptake in rat liver mitochondria have been studied using the potassium diffusion potential. The advantage of this approach is that in this condition, the mitochondrial respiratory rate is not the limiting step, and therefore the effects of Ni++ on the Ca++ carrier can be studied. Our results suggest that Ni++ is a competitive inhibitor of the Ca++ carrier, but it is not transported into the mitochondria.

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Year:  1997        PMID: 9161009     DOI: 10.1016/s0162-0134(96)00207-3

Source DB:  PubMed          Journal:  J Inorg Biochem        ISSN: 0162-0134            Impact factor:   4.155


  4 in total

1.  Involvement of mitochondrial Na+-Ca2+ exchange in intestinal pacemaking activity.

Authors:  Byung Joo Kim; Jae Yeoul Jun; Insuk So; Ki Whan Kim
Journal:  World J Gastroenterol       Date:  2006-02-07       Impact factor: 5.742

2.  Pacemaker frequency is increased by sodium nitroprusside in the guinea pig gastric antrum.

Authors:  Yoshihiko Kito; Hikaru Suzuki
Journal:  J Physiol       Date:  2003-01-01       Impact factor: 5.182

3.  Mitochondrial respiratory chain inhibition and Na+K+ATPase dysfunction are determinant factors modulating the toxicity of nickel in the brain of indian catfish Clarias batrachus L.

Authors:  Arpan Kumar Maiti; Nimai Chandra Saha; Goutam Paul; Kishore Dhara
Journal:  Interdiscip Toxicol       Date:  2019-10-18

4.  Mitochondrial Ca2+ uptake from plasma membrane Cav3.2 protein channels contributes to ischemic toxicity in PC12 cells.

Authors:  Yves Gouriou; Philippe Bijlenga; Nicolas Demaurex
Journal:  J Biol Chem       Date:  2013-03-18       Impact factor: 5.157

  4 in total

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