| Literature DB >> 9157102 |
G Klopman1, M Tu, J Talafous.
Abstract
META is a knowledge-based expert system that simulates the biotransformation of xenobiotics. It operates with the help of a dictionary (knowledge base) to seek target fragments in a compound and transform them to products. Here, a genetic algorithm is introduced to help build the knowledge base and optimize the performance of the methodology.Mesh：
Substances：
Year: 1997 PMID： 9157102 DOI： 10.1021/ci9601123
Source DB: PubMed Journal: J Chem Inf Comput Sci ISSN： 0095-2338