Literature DB >> 915511

Long-term effect of glucocorticosteroids on neuromuscular blocking in mice.

W F Arts, H J Oosterhuis.   

Abstract

The effect of dexamethasone, given thrice weekly, on neuromuscular blocking by D-tubocurarine was studied in mice. Dexamethasone antagonised the effect of D-tubocurarine. This antagonism developed gradually during the first two weeks of treatment. The possible relationship between this finding and the beneficial effect of glucocorticosteroids in patients with myasthenia gravis is discussed.

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Year:  1977        PMID： 915511      PMCID： PMC492798          DOI： 10.1136/jnnp.40.7.675

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN： 0022-3050            Impact factor:   10.154


  7 in total

1.  Glucocorticoids and mammalian motor nerve excitability.

Authors:  W F Riker; T Baker; M Okamoto
Journal:  Arch Neurol       Date:  1975-10

2.  The effect of corticosteroids and hemicholinium-3 on choline uptake and incorporation into acetylcholine in rat diaphragm.

Authors:  R D Veldsema-Currie; E Wolters; R S Leeuwin
Journal:  Eur J Pharmacol       Date:  1976-02       Impact factor: 4.432

3.  Effect of prednisolone on neuromuscular blocking in mice in vivo.

Authors:  W F Arts; H J Oosterhuis
Journal:  Neurology       Date:  1975-11       Impact factor: 9.910

4.  Benefit from alternate-day prednisone in myasthenia gravis.

Authors:  J R Warmolts; W K Engel
Journal:  N Engl J Med       Date:  1972-01-06       Impact factor: 91.245

5.  Myasthenia gravis: a serum factor blocking acetylcholine receptors of the human neuromuscular junction.

Authors:  A N Bender; S P Ringel; W K Engel; M P Daniels; Z Vogel
Journal:  Lancet       Date:  1975-03-15       Impact factor: 79.321

6.  Myasthenia gravis and acetylcholine receptor. Effect of steroids in clinical course and cellular immune response to acetylcholine receptor.

Authors:  O Abramsky; A Aharonov; D Teitelbaum; S Fuchs
Journal:  Arch Neurol       Date:  1975-10

7.  Effect of corticosteroids on the phrenic nerve-diaphragm of preparation treated with hemicholinium. A possible model of myasthenia gravis.

Authors:  M J Wolters; R S Leeuwin
Journal:  Neurology       Date:  1976-06       Impact factor: 9.910
  7 in total
  1 in total

1.  Effect of protracted dexamethasone exposure and its withdrawal on rocuronium-induced neuromuscular blockade and sugammadex reversal: an ex vivo rat study.

Authors:  Seok Kyeong Oh; Byung Gun Lim; Sungsoo Park; Hong Seuk Yang; Junyong In; Yong Beom Kim; Hey-Ran Choi; Il Ok Lee
Journal:  Sci Rep       Date:  2019-08-02       Impact factor: 4.379
  1 in total

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