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Literature DB >> 9155058

The influence of ifosfamide scheduling on acute nephrotoxicity in children.

M W English¹, R Skinner, A D Pearson, L Price, R Wyllie, A W Craft.

Abstract

Nephrotoxicity is a significant problem in children after treatment with ifosfamide. Acute changes in renal function were compared in 16 children receiving 9 g m(-2) of ifosfamide as a 72-h continuous infusion on one occasion and, on another course, divided into three 1-h infusions on consecutive days. Subclinical acute nephrotoxicity was demonstrated with both schedules, but there were no significant differences in severity.

Entities: Chemical Disease Species

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Year: 1997 PMID： 9155058 PMCID： PMC2228242 DOI： 10.1038/bjc.1997.229

Source DB: PubMed Journal: Br J Cancer ISSN： 0007-0920 Impact factor: 7.640

19 in total

1. Long-term follow-up of ifosfamide renal toxicity in children treated for malignant mesenchymal tumors: an International Society of Pediatric Oncology report.

Authors: A Suarez; H McDowell; P Niaudet; E Comoy; F Flamant
Journal: J Clin Oncol Date: 1991-12 Impact factor: 44.544

2. Ifosfamide, Fanconi's syndrome, and rickets.

Authors: C B Pratt; W H Meyer; J J Jenkins; L Avery; C P McKay; R J Wyatt; M L Hancock
Journal: J Clin Oncol Date: 1991-08 Impact factor: 44.544

3. Hyperaminoaciduria identifies patients at risk of developing renal tubular toxicity associated with ifosfamide and platinate containing regimens.

Authors: H N Caron; N Abeling; A van Gennip; J de Kraker; P A Voûte
Journal: Med Pediatr Oncol Date: 1992

Review 4. Assessment of chemotherapy-associated nephrotoxicity in children with cancer.

Authors: R Skinner; A D Pearson; M G Coulthard; A W Skillen; A W Hodson; M E Goldfinch; I Gibb; A W Craft
Journal: Cancer Chemother Pharmacol Date: 1991 Impact factor: 3.333

5. Progressive renal toxicity due to ifosfamide.

Authors: D Heney; J Wheeldon; P Rushworth; C Chapman; I J Lewis; C C Bailey
Journal: Arch Dis Child Date: 1991-08 Impact factor: 3.791

6. Ifosfamide nephrotoxicity: limited influence of metabolism and mode of administration during repeated therapy in paediatrics.

Authors: A V Boddy; M English; A D Pearson; J R Idle; R Skinner
Journal: Eur J Cancer Date: 1996-06 Impact factor: 9.162

The influence of ifosfamide scheduling on acute nephrotoxicity in children.

1. Long-term follow-up of ifosfamide renal toxicity in children treated for malignant mesenchymal tumors: an International Society of Pediatric Oncology report.

2. Ifosfamide, Fanconi's syndrome, and rickets.

3. Hyperaminoaciduria identifies patients at risk of developing renal tubular toxicity associated with ifosfamide and platinate containing regimens.

Review 4. Assessment of chemotherapy-associated nephrotoxicity in children with cancer.

5. Progressive renal toxicity due to ifosfamide.

6. Ifosfamide nephrotoxicity: limited influence of metabolism and mode of administration during repeated therapy in paediatrics.

7. Ifosfamide-induced Fanconi's syndrome with growth failure in a 2-year-old child.

8. Tubular function and histological findings in ifosfamide-induced renal Fanconi syndrome--a report of two cases.

9. Response to ifosfamide and mesna: 124 previously treated patients with metastatic or unresectable sarcoma.

10. The influence of age on nephrotoxicity following chemotherapy in children.

Review 1. Anticancer drug-induced kidney disorders.