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Literature DB >> 915502

Dopamine formation from phenylalanine: independent existence in caudate nucleus synaptosomes.

Abstract

Dopa and dopamine formations from phenylalanine and tyrosine in rat caudate nucleus synaptosomal preparation were studied. Phenylalanine and tyrosine, labelled with either 14C or 3H, were employed as cosubstrates leading to the formations of double labelled Dopa and dopamine. The ratio of the two isotopes in dopamine was found to be significantly different from that in Dopa. The results suggest that Dopa formed from the cosubstrates are compartmented.

Entities: Chemical Species

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Year: 1977 PMID： 915502 DOI： 10.1007/bf01670275

Source DB: PubMed Journal: J Neural Transm Impact factor: 3.575

13 in total

1. Decarboxylation of newly formed DOPA by caudate nucleus synaptosomal particles.

Authors: S P Bagchi; T M Smith
Journal: Brain Res Date: 1976-05-14 Impact factor: 3.252

2. Tyrosine hydroxylase in rat brain--cofactor requirements, regional and subcellular distribution.

Authors: J T Coyle
Journal: Biochem Pharmacol Date: 1972-07-15 Impact factor: 5.858

3. Heterogeneity of striatal and limbic dopamine innervation: highly fluorescent islands in developing and adult rats.

Authors: L Olson; A Seiger; K Fuxe
Journal: Brain Res Date: 1972-09-15 Impact factor: 3.252

4. In vivo formation of tyrosine from phenylalanine in brain.

Authors: S P Bagchi; E P Zarycki
Journal: Life Sci I Date: 1970-01-15

5. Solubilization and partial purification of tyrosine hydroxylase from bovine adrenal medulla.

Authors: R Shiman; M Akino; S Kaufman
Journal: J Biol Chem Date: 1971-03-10 Impact factor: 5.157

6. Subcellular localization of tyrosine hydroxylase in beef caudate nucleus.

Authors: P L McGeer; S P Bagchi; E G McGeer
Journal: Life Sci Date: 1965-10 Impact factor: 5.037

7. Formation of catecholamines from phenylalanine in brain--effects of chlorpromazine and catron.

Authors: S P Bagchi; E P Zarycki
Journal: Biochem Pharmacol Date: 1973-06-01 Impact factor: 5.858

8. Formation of catechol compounds from phenylalanine and tyrosine with isolated nerve endings.

Authors: M Karobath; R J Baldessarini
Journal: Nat New Biol Date: 1972-04-19

9. Microfluorimetric quantitation of catecholamine fluorescence in rat median eminence. II. Turnover changes in hormonal states.

Authors: A Löfström; G Jonsson; F A Wiesel; K Fuxe
Journal: J Histochem Cytochem Date: 1976-02 Impact factor: 2.479

10. The distribution and rates of formation of catecholamines in several regions of bovine brain.

Authors: E P Kindwall; N Weiner
Journal: J Neurochem Date: 1966-12 Impact factor: 5.372

1 in total

1. Changes in the neurochemistry of athletes with repetitive brain trauma: preliminary results using localized correlated spectroscopy.

Authors: Alexander P Lin; Saadallah Ramadan; Robert A Stern; Hayden C Box; Christopher J Nowinski; Brian D Ross; Carolyn E Mountford
Journal: Alzheimers Res Ther Date: 2015-03-15 Impact factor: 6.982

1 in total