Literature DB >> 9154201

A review of the progress in canine hip dysplasia control in Britain.

M B Willis1.   

Abstract

Results of the British Veterinary Association/Kennel Club program for controlling canine hip dysplasia (CHD) were reviewed for 6 breeds to determine whether there had been any progress in reducing the prevalence of CHD. Although there was a decrease in mean hip dysplasia score for some of the 6 breeds when results for the 1991 to 1995 period were compared with those for 1987 to 1990, there were not any consistent trends in 5 of the breeds, and there was a clear worsening of the mean hip score in Siberian Huskies. In general terms, not only has there been a steady increase in the percentage of parents that were scored or, more accurately, an increase in the use of scored parents when breeding, but in broad terms the weighted mean score for the parents was lower (ie, better) than the mean score for all dogs in the breed during each period. In all breeds, there appeared to have been some selection to reduce total hip score, but in all but 1 instance, the expected result was not achieved, with actual values being higher (ie, worse) than those expected from theory. If the incidence of CHD is to diminish in Britain, then, as a first step, the Kennel Club must insist that, in affected breeds, only progeny of scored parents may be registered. Thereafter, a gradual tightening of the parental scores that will be accepted in each breed should be attempted, and best linear unbiased predictor-type indices should be established and applied to sires and dams to ensure wider usage of the better parents.

Entities:  

Mesh:

Year:  1997        PMID: 9154201

Source DB:  PubMed          Journal:  J Am Vet Med Assoc        ISSN: 0003-1488            Impact factor:   1.936


  10 in total

1.  The association of genetic polymorphisms of bone formation genes with canine hip dysplasia.

Authors:  I Akis; A Ates; G Atmaca; K O Oztabak; F Esen Gursel; H Yardibi; K Altunatmaz; E Eravci Yalin; M Karabagli
Journal:  Iran J Vet Res       Date:  2020       Impact factor: 1.376

2.  Genetic evaluation of hip score in UK Labrador Retrievers.

Authors:  Thomas W Lewis; Sarah C Blott; John A Woolliams
Journal:  PLoS One       Date:  2010-10-22       Impact factor: 3.240

3.  Genetic evaluation of the nine component features of hip score in UK Labrador Retrievers.

Authors:  Thomas W Lewis; John A Woolliams; Sarah C Blott
Journal:  PLoS One       Date:  2010-10-22       Impact factor: 3.240

4.  Genomic prediction of traits related to canine hip dysplasia.

Authors:  Enrique Sánchez-Molano; Ricardo Pong-Wong; Dylan N Clements; Sarah C Blott; Pamela Wiener; John A Woolliams
Journal:  Front Genet       Date:  2015-03-13       Impact factor: 4.599

5.  Quantitative trait loci mapping for canine hip dysplasia and its related traits in UK Labrador Retrievers.

Authors:  Enrique Sánchez-Molano; John A Woolliams; Ricardo Pong-Wong; Dylan N Clements; Sarah C Blott; Pamela Wiener
Journal:  BMC Genomics       Date:  2014-10-01       Impact factor: 3.969

6.  A genetic predictive model for canine hip dysplasia: integration of Genome Wide Association Study (GWAS) and candidate gene approaches.

Authors:  Nerea Bartolomé; Sergi Segarra; Marta Artieda; Olga Francino; Elisenda Sánchez; Magdalena Szczypiorska; Joaquim Casellas; Diego Tejedor; Joaquín Cerdeira; Antonio Martínez; Alfonso Velasco; Armand Sánchez
Journal:  PLoS One       Date:  2015-04-13       Impact factor: 3.240

7.  Genomic data illuminates demography, genetic structure and selection of a popular dog breed.

Authors:  Pamela Wiener; Enrique Sánchez-Molano; Dylan N Clements; John A Woolliams; Marie J Haskell; Sarah C Blott
Journal:  BMC Genomics       Date:  2017-08-14       Impact factor: 3.969

8.  Comparative analyses of genetic trends and prospects for selection against hip and elbow dysplasia in 15 UK dog breeds.

Authors:  Thomas W Lewis; Sarah C Blott; John A Woolliams
Journal:  BMC Genet       Date:  2013-03-02       Impact factor: 2.797

9.  Assessing the impact of genomic selection against hip dysplasia in the Labrador Retriever dog.

Authors:  E Sánchez-Molano; J A Woolliams; S C Blott; P Wiener
Journal:  J Anim Breed Genet       Date:  2013-10-18       Impact factor: 2.380

10.  Joint Genomic Prediction of Canine Hip Dysplasia in UK and US Labrador Retrievers.

Authors:  Stefan M Edwards; John A Woolliams; John M Hickey; Sarah C Blott; Dylan N Clements; Enrique Sánchez-Molano; Rory J Todhunter; Pamela Wiener
Journal:  Front Genet       Date:  2018-03-28       Impact factor: 4.599

  10 in total

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