Literature DB >> 9153786

The GCMS analysis of tranylcypromine (Parnate) in a suspected overdose.

J Crifasi1, C Long.   

Abstract

A fatal overdose involving tranylcypromine (Parnate) where blood, urine and tissues were quantitated using a pentafluoroproprionic anhydride (PFPA) derivative and gas-chromatography/mass spectroscopy (GCMS). The samples were re-quantified over several weeks demonstrating a significant loss of drug in tissues but not blood or urine specimens. The urine was positive for methamphetamine which has been a suspected metabolite.

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Year:  1997        PMID: 9153786     DOI: 10.1016/s0379-0738(97)02126-9

Source DB:  PubMed          Journal:  Forensic Sci Int        ISSN: 0379-0738            Impact factor:   2.395


  2 in total

Review 1.  Neurochemical and metabolic aspects of antidepressants: an overview.

Authors:  G B Baker; R T Coutts; A J Greenshaw
Journal:  J Psychiatry Neurosci       Date:  2000-11       Impact factor: 6.186

2.  Discrimination Between Drug Abuse and Medical Therapy: Case report of a tranylcypromine overdose-related fatality.

Authors:  Maryam Akhgari; Farzaneh Jokar; Afshar Etemadi-Aleagha; Ali Ghasemi
Journal:  Sultan Qaboos Univ Med J       Date:  2017-06-20
  2 in total

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