| Literature DB >> 9153447 |
G Fenichel1, A Pestronk, J Florence, V Robison, V Hemelt.
Abstract
We treated 10 boys with Duchenne muscular dystrophy with oxandrolone, an anabolic steroid, for 3 months. The mean of the changes in the average muscle score was an improvement of 0.315 +/- 0.097. The expected mean change in muscle score after 3 months from natural history data is a loss of 0.1. The difference of 0.415 between the actual and expected values is significant at p < 0.01. This preliminary evidence suggests that oxandrolone treatment may provide a degree of functional benefit for children with Duchenne muscular dystrophy that is similar to that after prednisone administration.Entities:
Mesh：
Substances：
Year: 1997 PMID： 9153447 DOI： 10.1212/wnl.48.5.1225
Source DB: PubMed Journal: Neurology ISSN： 0028-3878 Impact factor: 9.910