Literature DB >> 9153144

Exploring the potential of DNA vaccination.

I R Cohen1, L Steinman.   

Abstract

DNA vaccines offer a unique means of stimulating and enhancing the immune response. Subjects are vaccinated with the gene for a particular antigen rather than with the antigen itself--the foreign protein that elicits the response is made intracellularly. This new type of gene therapy may not only extend the limits of immunoprotection but may also provide new insight into microbiologic and immunologic processes.

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Year:  1997        PMID: 9153144     DOI: 10.1080/21548331.1997.11443488

Source DB:  PubMed          Journal:  Hosp Pract (1995)        ISSN: 2154-8331


  3 in total

Review 1.  Genetic vaccines: strategies for optimization.

Authors:  G Gregoriadis
Journal:  Pharm Res       Date:  1998-05       Impact factor: 4.200

Review 2.  Gene therapy in experimental autoimmune encephalomyelitis.

Authors:  P M Mathisen; V K Tuohy
Journal:  J Clin Immunol       Date:  2000-09       Impact factor: 8.317

3.  Microbial epitopes act as altered peptide ligands to prevent experimental autoimmune encephalomyelitis.

Authors:  P J Ruiz; H Garren; D L Hirschberg; A M Langer-Gould; M Levite; M V Karpuj; S Southwood; A Sette; P Conlon; L Steinman
Journal:  J Exp Med       Date:  1999-04-19       Impact factor: 14.307

  3 in total

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