Marked decrease in intraocular pressure in a neovascular glaucoma patient during hemodialysis.

While the relationship between intraocular pressure and plasma osmolarity has been investigated during hemodialysis, no research has been published concerning the relationship between intraocular pressure and plasma colloid osmotic pressure during hemodialysis. We describe a patient with neovascular glaucoma who demonstrated a marked decrease in intraocular pressure during hemodialysis. The patient's intraocular pressure, plasma osmolarity, plasma colloid osmotic pressure, and body weight were evaluated every 30 minutes during hemodialysis lasting 4.5 hours. Plasma osmolarity was almost constant during hemodialysis (beginning: 295 mOsm/L; ending: 305 mOsm/L), and plasma colloid osmotic pressure increased (beginning: 23.0 mm Hg; peak: 27.2 mm Hg). Weight loss was 5.7 kg. Intraocular pressure decreased markedly during hemodialysis (beginning: 53 mm Hg; ending: 14 mm Hg). This sharp decrease in intraocular pressure and the increase in plasma colloid osmotic pressure, indicate a relationship between plasma colloid osmotic pressure and the change in intraocular pressure during hemodialysis.