| Literature DB >> 9152296 |
J P Barcia1, C F Strife, C B Langman.
Abstract
A 2-month-old child with infantile hypophosphatasia had hypercalcemia (3.49 mmol/L (14 mg/dl)), nephrocalcinosis, and diminished bone mineral content. Hypercalcemia was corrected with calcitonin. Hypercalciuria and bone demineralization abated with chlorothiazide. Hypercalcemia is hypothesized to be related to normal bone resorption in conjunction with impaired bone mineralization. Chlorothiazide may alleviate this impairment.Entities:
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Year: 1997 PMID： 9152296 DOI： 10.1016/s0022-3476(97)80029-7
Source DB: PubMed Journal: J Pediatr ISSN： 0022-3476 Impact factor: 4.406