Literature DB >> 9151347

The anaesthetist as determinant factor of quality of surgical antimicrobial prophylaxis. A survey in a university hospital.

I C Gyssens1, J T Knape, G Van Hal, J W ver der Meer.   

Abstract

In actual surgical antimicrobial prophylaxis, the anaesthetist administers the drugs at induction of anaesthesia. In the first phase of our quality-of-use intervention study on antimicrobial drugs in a large university hospital, information on the practice of antimicrobial prophylaxis was needed. The staff of 44 anaesthetists was interviewed by means of a questionnaire. Response rate was 36/44 (82%). The anaesthetists' method of administering surgical prophylaxis was rather uniform and inexpensive: cephalosporins were almost exclusively administered by bolus method. The main reason was that infusion was more cumbersome (range 77-85%). Communication between surgeon and anaesthetist was reported to be poor, and in two out of three operating departments, orders of prophylaxis transmitted at or after induction accounted for more than 80%. Seventy-seven percent of the responders asked the surgeon if prophylaxis was necessary if they were in doubt; 20% responded that they checked it systematically. The data collected by the inquiry proved useful in the process of optimizing surgical prophylaxis in our hospital.

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Year:  1997        PMID: 9151347     DOI: 10.1023/a:1008691007436

Source DB:  PubMed          Journal:  Pharm World Sci        ISSN: 0928-1231


  7 in total

Review 1.  Once-daily aminoglycoside therapy.

Authors:  D N Gilbert
Journal:  Antimicrob Agents Chemother       Date:  1991-03       Impact factor: 5.191

2.  The timing of prophylactic administration of antibiotics and the risk of surgical-wound infection.

Authors:  D C Classen; R S Evans; S L Pestotnik; S D Horn; R L Menlove; J P Burke
Journal:  N Engl J Med       Date:  1992-01-30       Impact factor: 91.245

3.  Cost of hospital antimicrobial chemotherapy. A method for global cost calculation.

Authors:  I C Gyssens; C A Lennards; Y A Hekster; J W Van der Meer
Journal:  Pharm Weekbl Sci       Date:  1991-12-13

4.  Optimizing the timing of antimicrobial prophylaxis in surgery: an intervention study.

Authors:  I C Gyssens; I E Geerligs; M G Nannini-Bergman; J T Knape; Y A Hekster; J W van der Meer
Journal:  J Antimicrob Chemother       Date:  1996-08       Impact factor: 5.790

5.  Optimising antimicrobial drug use in surgery: an intervention study in a Dutch university hospital.

Authors:  I C Gyssens; I E Geerligs; J M Dony; J A van der Vliet; A van Kampen; P J van den Broek; Y A Hekster; J W van der Meer
Journal:  J Antimicrob Chemother       Date:  1996-12       Impact factor: 5.790

6.  Safety of the bolus administration of gentamicin.

Authors:  J Mendelson; J Portnoy; V Dick; M Black
Journal:  Antimicrob Agents Chemother       Date:  1976-04       Impact factor: 5.191

7.  Antimicrobial prophylaxis in surgery.

Authors: 
Journal:  Med Lett Drugs Ther       Date:  1989-12-01       Impact factor: 1.909

  7 in total
  3 in total

Review 1.  Preventing postoperative infections: current treatment recommendations.

Authors:  I C Gyssens
Journal:  Drugs       Date:  1999-02       Impact factor: 9.546

2.  In vitro testing of antimicrobial activity of bone cement.

Authors:  Volker Alt; Thorsten Bechert; Peter Steinrücke; Michael Wagener; Peter Seidel; Elvira Dingeldein; Eugen Domann; Reinhard Schnettler
Journal:  Antimicrob Agents Chemother       Date:  2004-11       Impact factor: 5.191

Review 3.  [Perioperative antibiotic prophylaxis. Use in orthopaedics].

Authors:  M Széll; S Hofmann; M Pietsch; E Gerhart; C Wenisch
Journal:  Orthopade       Date:  2006-07       Impact factor: 1.087

  3 in total

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