| Literature DB >> 91511 |
T Pertynski, G Reznik, P Mariss, M B Ketkar, H Haindl, G Dieffenbach.
Abstract
Organ distribution and tumor uptake of 57Co-bleomycin (BLM) were examined in NMRI mice without tumor and with chemically (DMBA-) induced squamous cell carcinoma. In these tumors high accumulation of 57Co-BLM was recorded shortly after injection of 57Co-BLM and low uptake 24--48 h after application. Two groups of tumor-bearing mice received unlabeled bleomycin as a cytostatic in two different doses. Uptake of 57Co-bleomycin was reduced. The study suggests that in patients currently or previously under chemotherapy, 57Co-bleomycin tumor scintigraphy may lead to false negative results.Entities:
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Year: 1979 PMID： 91511 DOI： 10.1007/BF00257571
Source DB: PubMed Journal: Eur J Nucl Med ISSN： 0340-6997