Literature DB >> 9151013

Altered calcium homeostasis in the rat cochlear duct and endogenous corticosteroid insufficiency.

Y L Ma1, K E Rarey, K J Gerhardt, L C Garg, L P Rybak.   

Abstract

Free calcium concentration (CCa2+) profiles were evaluated in perilymph, endolymph, marginal cells, spiral ligament and blood serum of adrenalectomized (ADX) rats. Free CCa2+ was significantly greater in perilymph and significantly reduced in the serum of the ADX animals as compared to sham-operated animals. In addition, higher levels of free CCa2+ were found in the spiral ligament in ADX animals. Free CCa2+ did not appear to be affected by ADX in marginal cells and endolymph. These data suggest that marked reductions in endogenous levels of corticosteroids may have a systematic effect on free CCa2+ that is detectable in blood serum as well as cochlear fluids and tissues.

Entities:  

Mesh：

Substances：

Year:  1997        PMID： 9151013     DOI： 10.1007/bf00879267

Source DB:  PubMed          Journal:  Eur Arch Otorhinolaryngol        ISSN： 0937-4477            Impact factor:   2.503


  23 in total

1.  The cellular basis of hearing: the biophysics of hair cells.

Authors:  A J Hudspeth
Journal:  Science       Date:  1985-11-15       Impact factor: 47.728

2.  In situ real-time sequential potentiometric determinations of potassium concentrations from three cochlear regions in noise-exposed rats.

Authors:  Y L Ma; K J Gerhardt; L P Rybak; L M Curtis; K E Rarey
Journal:  Eur Arch Otorhinolaryngol       Date:  1996       Impact factor: 2.503

3.  Electrochemical potentials and potassium concentration profiles recorded from perilymph, endolymph and associated inner ear tissues in adrenalectomized rats.

Authors:  Y L Ma; K E Rarey; K J Gerhardt; L M Curtis; L P Rybak
Journal:  Hear Res       Date:  1996-07       Impact factor: 3.208

4.  Electrochemical profile for calcium ions in the stria vascularis: cellular model of calcium transport mechanism.

Authors:  K Ikeda; T Morizono
Journal:  Hear Res       Date:  1989-06-15       Impact factor: 3.208

5.  Ionic composition of the endolymph and sensory transduction in labyrinthine organs.

Authors:  P Valli; G Zucca; C Casella
Journal:  Acta Otolaryngol       Date:  1979 May-Jun       Impact factor: 1.494

6.  Neutral carrier ion-selective microelectrodes for measurement of intracellular free calcium.

Authors:  R Y Tsien; T J Rink
Journal:  Biochim Biophys Acta       Date:  1980-07

7.  Time-related alteration of endolymph composition in an experimental model of endolymphatic hydrops.

Authors:  I Sziklai; E Ferrary; K C Horner; O Sterkers; C Amiel
Journal:  Laryngoscope       Date:  1992-04       Impact factor: 3.325

8.  Mechano-electrical transduction currents in isolated vestibular hair cells of the chick.

Authors:  H Ohmori
Journal:  J Physiol       Date:  1985-02       Impact factor: 5.182

9.  Endolymph calcium increases with time after surgical induction of hydrops in guinea-pigs.

Authors:  A N Salt; J DeMott
Journal:  Hear Res       Date:  1994-04       Impact factor: 3.208

10.  Calcium transport mechanism in the endolymph of the chinchilla.

Authors:  K Ikeda; T Morizono
Journal:  Hear Res       Date:  1988-08       Impact factor: 3.208
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.