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Literature DB >> 914894

Studies of the secretory process in the mammalian exocrine pancreas. I. The condensing vacuoles.

A B Novikoff, M Mori, N Quintana, A Yam.

Abstract

Phosphatase cytochemistry was used to distinguish between the Golgi apparatus and GERL (considered as a specialized region of endoplasmic reticulum [ER] at the inner [trans] aspect of the Golgi stack) in pancreatic exocrine cells of guinea pig, rat, rabbit, and hamster. The trans element of the Golgi stack exhibits thiamine pyrophosphatase (TPPase) but no acid phosphatase (AcPase) activity. In contrast, GERL shows AcPase but no TPPase activity. The nascent secretory granules, or condensing vacuoles, are expanded cisternal portions of GERL. Continuities of condensing vacuoles with rough ER are suggested, and it is proposed that some secretory components may have direct access to the condensing vacuoles from ER. Connections of Golgi apparatus with GERL were not seen.

Entities: Disease Species

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Year: 1977 PMID： 914894 PMCID： PMC2111565 DOI： 10.1083/jcb.75.1.148

Source DB: PubMed Journal: J Cell Biol ISSN： 0021-9525 Impact factor: 10.539

26 in total

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Journal: J R Microsc Soc Date: 1963-10

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Journal: J Cell Biol Date: 1977-08 Impact factor: 10.539

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Authors: E S REYNOLDS
Journal: J Cell Biol Date: 1963-04 Impact factor: 10.539

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Journal: J Biophys Biochem Cytol Date: 1956-07-25

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Journal: J Cell Biol Date: 1973-10 Impact factor: 10.539

10. Synthesis, migration, and release of precursor collagen by odontoblasts as visualized by radioautography after (3H)proline administration.

Authors: M Weinstock; C P Leblond
Journal: J Cell Biol Date: 1974-01 Impact factor: 10.539

39 in total

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Authors: F Sawano; H Fujita
Journal: Histochemistry Date: 1981

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Authors: M Bendayan
Journal: Histochem J Date: 1984-01

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Authors: B F Fell; T P King; N T Davies
Journal: Histochem J Date: 1982-07

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Authors: Y S Kanwar; L J Rosenzweig; M L Jakubowski; J K Reddy
Journal: Proc Natl Acad Sci U S A Date: 1983-11 Impact factor: 11.205

10. Thiamine pyrophosphatase activity in secretory cells of the lateral prostate and seminal vesicle of normal and castrated guinea pigs and castrates treated with oestradiol.

Authors: C C Tam; Y C Wong
Journal: Histochem J Date: 1993-01