| Literature DB >> 914635 |
A M Dozy, H Kabisch, J Baker, H M Koenig, S Kurachi, G Stamatoyannopoulos, D Todd, Y W Kan.
Abstract
Molecular hybridization with synthetic radioactive DNA (cDNA) complementry to alpha globin mRNA sequences shows that, as in most other Southeast Asian populations, the alpha globin structural genes are deleted in Filipinos affected by the alpha-thalassemia syndromes. Thus, all 4 alpha-globin structural genes are deleted in homozygous alpha-thalassemia with hydrops fetalis, 3 and 2 structural genes are deleted in hemoglobin H disease and alpha-thalassemia-1 respectively.Entities:
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Year: 1977 PMID： 914635 DOI： 10.3109/03630267709003418
Source DB: PubMed Journal: Hemoglobin ISSN： 0363-0269 Impact factor: 0.849