Literature DB >> 9145899

In vitro activity of premafloxacin, a new extended-spectrum fluoroquinolone, against pathogens of veterinary importance.

J L Watts1, S A Salmon, M S Sanchez, R J Yancey.   

Abstract

The in vitro activity of premafloxacin against 673 veterinary pathogens was evaluated. Premafloxacin was equivalent to ciprofloxacin, enrofloxacin, and danofloxacin in activity against the gram-negative bacilli but was much more active (MIC for 90% of the strains tested [MIC90], 0.015 to 0.25 microg/ml) than the comparison antimicrobial agents (MIC90, 0.13 to 16.0 microg/ml) against the staphylococci, streptococci, and anaerobes tested.

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Year:  1997        PMID： 9145899      PMCID： PMC163880     

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  6 in total

1.  Efficacy of danofloxacin in the therapy of acute bacterial pneumonia in housed beef cattle.

Authors:  C J Giles; W T Grimshaw; D J Shanks; D G Smith
Journal:  Vet Rec       Date:  1991-03-30       Impact factor: 2.695

2.  Premafloxacin: a projected veterinary use fluoro-quinolone with significant activity against multi-resistant gram-positive human pathogens.

Authors:  L Zerva; S A Marshall; R N Jones
Journal:  J Antimicrob Chemother       Date:  1996-10       Impact factor: 5.790

Review 3.  Fluoroquinolones in animal health.

Authors:  S A Brown
Journal:  J Vet Pharmacol Ther       Date:  1996-02       Impact factor: 1.786

4.  A 4-year survey of antimicrobial susceptibility trends for isolates from cattle with bovine respiratory disease in North America.

Authors:  J L Watts; R J Yancey; S A Salmon; C A Case
Journal:  J Clin Microbiol       Date:  1994-03       Impact factor: 5.948

5.  Evaluation of antibacterial agents in a high-volume bovine polymorphonuclear neutrophil Staphylococcus aureus intracellular killing assay.

Authors:  M S Sanchez; C W Ford; R J Yancey
Journal:  Antimicrob Agents Chemother       Date:  1986-04       Impact factor: 5.191

6.  Comparison of MICs of ceftiofur and other antimicrobial agents against bacterial pathogens of swine from the United States, Canada, and Denmark.

Authors:  S A Salmon; J L Watts; C A Case; L J Hoffman; H C Wegener; R J Yancey
Journal:  J Clin Microbiol       Date:  1995-09       Impact factor: 5.948
  6 in total
  7 in total

1.  Genotypic analysis of Escherichia coli strains from poultry carcasses and their susceptibilities to antimicrobial agents.

Authors:  I Geornaras; J W Hastings; A von Holy
Journal:  Appl Environ Microbiol       Date:  2001-04       Impact factor: 4.792

2.  MICs of oxazolidinones for Rhodococcus equi strains isolated from humans and animals.

Authors:  T L Bowersock; S A Salmon; E S Portis; J F Prescott; D A Robison; C W Ford; J L Watts
Journal:  Antimicrob Agents Chemother       Date:  2000-05       Impact factor: 5.191

3.  Effects of enrofloxacin on porcine phagocytic function.

Authors:  E J Schoevers; L A van Leengoed; J H Verheijden; T A Niewold
Journal:  Antimicrob Agents Chemother       Date:  1999-09       Impact factor: 5.191

4.  Susceptibilities of Corynebacterium bovis and Corynebacterium amylocolatum isolates from bovine mammary glands to 15 antimicrobial agents.

Authors:  J L Watts; S Rossbach
Journal:  Antimicrob Agents Chemother       Date:  2000-12       Impact factor: 5.191

5.  Mechanisms and frequency of resistance to premafloxacin in Staphylococcus aureus: novel mutations suggest novel drug-target interactions.

Authors:  D Ince; D C Hooper
Journal:  Antimicrob Agents Chemother       Date:  2000-12       Impact factor: 5.191

6.  Quinolone resistance due to reduced target enzyme expression.

Authors:  Dilek Ince; David C Hooper
Journal:  J Bacteriol       Date:  2003-12       Impact factor: 3.490

7.  Disposition kinetics and urinary excretion of ciprofloxacin in goats following single intravenous administration.

Authors:  R Raina; S Prawez; D J Dimitrova; N K Pankaj; P K Verma
Journal:  J Vet Sci       Date:  2008-09       Impact factor: 1.672
  7 in total

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