Literature DB >> 9145896

Efficacies of ofloxacin, rifampin, and clindamycin in treatment of Staphylococcus aureus abscesses and correlation with results of an in vitro assay of intracellular bacterial killing.

D M Bamberger1, B L Herndon, M Dew, R P Chern, H Mitchell, L E Summers, R F Marcus, S C Kim, P R Suvarna.   

Abstract

We studied the efficacies of ofloxacin, rifampin, and clindamycin in a Staphylococcus aureus abscess model and seven antimicrobial regimens in an intracellular killing assay. Ofloxacin plus rifampin was the most effective regimen in the abscess model, and rifampin and ofloxacin were the most active regimens in the intracellular killing assay.

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Year:  1997        PMID： 9145896      PMCID： PMC163877     

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  19 in total

1.  Killing of intraleukocytic Staphylococcus aureus by rifampin: in-vitro and in-vivo studies.

Authors:  G L Mandell; T K Vest
Journal:  J Infect Dis       Date:  1972-05       Impact factor: 5.226

2.  Effects of subinhibitory concentrations of antibiotics on Staphylococcus aureus interactions with fibronectin.

Authors:  R A Proctor; R J Hamill; D F Mosher; J A Textor; P J Olbrantz
Journal:  J Antimicrob Chemother       Date:  1983-10       Impact factor: 5.790

3.  Azithromycin in an experimental Staphylococcus aureus abscess model.

Authors:  D M Bamberger; B L Herndon; P R Suvarna
Journal:  J Antimicrob Chemother       Date:  1995-05       Impact factor: 5.790

4.  Contrasts between phagocyte antibiotic uptake and subsequent intracellular bactericidal activity.

Authors:  W L Hand; N L King-Thompson
Journal:  Antimicrob Agents Chemother       Date:  1986-01       Impact factor: 5.191

5.  Intraleukocytic sequestration as a cause of persistent Staphylococcus aureus peritonitis in continuous ambulatory peritoneal dialysis.

Authors:  B P Buggy; D R Schaberg; R D Swartz
Journal:  Am J Med       Date:  1984-06       Impact factor: 4.965

6.  Evaluation of antibiotic effectiveness against Staphylococcus aureus surviving within the bovine mammary gland macrophage.

Authors:  M S Sanchez; C W Ford; R J Yancey
Journal:  J Antimicrob Chemother       Date:  1988-06       Impact factor: 5.790

7.  Rifampin in the treatment of serious staphylococcal infections.

Authors:  L Swanberg; C U Tuazon
Journal:  Am J Med Sci       Date:  1984 May-Jun       Impact factor: 2.378

8.  Intracellular penetration and antimicrobial activity of antibiotics.

Authors:  R F Jacobs; C B Wilson
Journal:  J Antimicrob Chemother       Date:  1983-10       Impact factor: 5.790

Review 9.  Lessons learned from animal models of osteomyelitis.

Authors:  C W Norden
Journal:  Rev Infect Dis       Date:  1988 Jan-Feb

10.  Determination of minimum bactericidal concentrations of oxacillin for Staphylococcus aureus: influence and significance of technical factors.

Authors:  P C Taylor; F D Schoenknecht; J C Sherris; E C Linner
Journal:  Antimicrob Agents Chemother       Date:  1983-01       Impact factor: 5.191
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  4 in total

1.  Effect of a single percutaneous abscess drainage puncture and imipenem therapy, alone or in combination, in treatment of mixed-infection abscesses in mice.

Authors:  Lorna E T Stearne; Steven L Buijk; Johan W Mouton; Inge C Gyssens
Journal:  Antimicrob Agents Chemother       Date:  2002-12       Impact factor: 5.191

2.  Comparison of efficacies of oral levofloxacin and oral ciprofloxacin in a rabbit model of a staphylococcal abscess.

Authors:  J Fernandez; J F Barrett; L Licata; D Amaratunga; M Frosco
Journal:  Antimicrob Agents Chemother       Date:  1999-03       Impact factor: 5.191

3.  Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus small-colony variant strain isolated from a cystic fibrosis patient: study of antibiotic combinations.

Authors:  Hoang Anh Nguyen; Olivier Denis; Anne Vergison; Paul M Tulkens; Marc J Struelens; Françoise Van Bambeke
Journal:  Antimicrob Agents Chemother       Date:  2009-02-02       Impact factor: 5.191

4.  Effects of neutrophils on cefazolin activity and penicillin-binding proteins in Staphylococcus aureus abscesses.

Authors:  David M Bamberger; Betty L Herndon; Jeffrey Fitch; Aaron Florkowski; Vera Parkhurst
Journal:  Antimicrob Agents Chemother       Date:  2002-09       Impact factor: 5.191
  4 in total

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