Literature DB >> 9145504

Synthesis and hypolipidemic activity of diesters of arylnaphthalene lignan and their heteroaromatic analogs.

T Kuroda1, K Kondo, T Iwasaki, A Ohtani, K Takashima.   

Abstract

A series of diesters of arylnaphthalene lignan and their heteroaromatic analogs were synthesized and evaluated for hypolipidemic activity. The disasters with modifications at C-3 showed excellent hypocholesterolemic and high-density lipoprotein (HDL) cholesterol-elevating activities. Structure-activity analysis indicated that the 2-pyridylmethyl ester 5l has the optimum activity.

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Year:  1997        PMID： 9145504     DOI： 10.1248/cpb.45.678

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN： 0009-2363            Impact factor:   1.645


  2 in total

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Authors:  Raluca Ecaterina Haliga; Roxana Irina Iancu; Doina Butcovan; Veronica Mocanu
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Journal:  Evid Based Complement Alternat Med       Date:  2015-07-12       Impact factor: 2.629
  2 in total

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