Literature DB >> 9145104

Three-dimensional structure of staphylokinase, a plasminogen activator with therapeutic potential.

A Rabijns, H L De Bondt, C De Ranter.   

Abstract

The three-dimensional structure of staphylokinase has been determined at 1.8 A. The puntative site of interaction with plasminogen was identified and epitopes were mapped.

Mesh：

Substances：

Year:  1997        PMID： 9145104     DOI： 10.1038/nsb0597-357

Source DB:  PubMed          Journal:  Nat Struct Biol        ISSN： 1072-8368


  14 in total

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2.  Function of the 90-loop (Thr90-Glu100) region of staphylokinase in plasminogen activation probed through site-directed mutagenesis and loop deletion.

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3.  Structural basis for reduced staphylocoagulase-mediated bovine prothrombin activation.

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4.  Staphylokinase as a plasminogen activator component in recombinant fusion proteins.

Authors:  S J Szarka; E G Sihota; H R Habibi; S Wong
Journal:  Appl Environ Microbiol       Date:  1999-02       Impact factor: 4.792

Review 5.  The natural history of ubiquitin and ubiquitin-related domains.

Authors:  Alexander Maxwell Burroughs; Lakshminarayan M Iyer; L Aravind
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7.  Psychosocial risk factors of myocardial infarction and adverse effects of streptokinase in public sector hospitals.

Authors:  Saira Afzal; Muhammad Arif Khan; Hafiz Muhammad; Ayesha Ashraf; Maria Afzal
Journal:  Pak J Med Sci       Date:  2015 Jul-Aug       Impact factor: 1.088

Review 8.  Bacterial plasminogen receptors utilize host plasminogen system for effective invasion and dissemination.

Authors:  Sarbani Bhattacharya; Victoria A Ploplis; Francis J Castellino
Journal:  J Biomed Biotechnol       Date:  2012-10-14

9.  Small but versatile: the extraordinary functional and structural diversity of the beta-grasp fold.

Authors:  A Maxwell Burroughs; S Balaji; Lakshminarayan M Iyer; L Aravind
Journal:  Biol Direct       Date:  2007-07-02       Impact factor: 4.540

10.  Characterization of a novel bifunctional mutant of staphylokinase with platelet-targeted thrombolysis and antiplatelet aggregation activities.

Authors:  Hongshan Chen; Wei Mo; Huabo Su; Yanling Zhang; Houyan Song
Journal:  BMC Mol Biol       Date:  2007-10-07       Impact factor: 2.946
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