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Literature DB >> 914275

The frequency and distribution of sister chromatid exchanges in human chromosomes.

Abstract

The distribution of sister chromatid exchanges (SCEs) both between and within chromosomes was studied in cultured human lymphocytes using the BRDU-Giemsa technique. In general, the distribution of SCEs between chromosomes was a function of chromosome length. However, chromosomes of the B group had more exchanges than expected on this basis, while the E, F, and G groups had less than expected. Analysis of cells showing both G-banding and sister chromatid differential staining indicates that the distribution of exchanges within the chromosomes is non-random and possible reasons for the observed distribution pattern are discussed.

Entities: Species

Mesh：

Year: 1977 PMID： 914275 DOI： 10.1007/bf00402152

Source DB: PubMed Journal: Hum Genet ISSN： 0340-6717 Impact factor: 4.132

30 in total

6. Presence of a base line level of sister chromatid exchanges in somatic cells of Drosophila melanogaster in vivo and in vitro.

Authors: H Tsuji
Journal: Genetics Date: 1982-02 Impact factor: 4.562

7. Sister chromatid exchanges and heterochromatin.

Authors: I Schubert; R Rieger
Journal: Hum Genet Date: 1981 Impact factor: 4.132

Review 8. Sister chromatid exchange (SCE) and structural chromosome aberration in mutagenicity testing.

Authors: E Gebhart
Journal: Hum Genet Date: 1981 Impact factor: 4.132

9. Selective differential staining of sister chromatids of the facultative heterochromatic X chromosome in the female mouse.

Authors: N Kanda
Journal: Chromosoma Date: 1981 Impact factor: 4.316

10. Sister chromatid exchange in cigarette smokers.

Authors: P E Crossen; W F Morgan
Journal: Hum Genet Date: 1980 Impact factor: 4.132

The frequency and distribution of sister chromatid exchanges in human chromosomes.

1. Nonrandom distribution of chromosome breaks in Fanconi's anemia.

2. Microfluorometric detection of deoxyribonucleic acid replication in human metaphase chromosomes.

3. Giemsa banding patterns of human chromosomes.

4. High resolution studies on the pattern of induced exchanges in the human karyotype.

5. Preferential location of x-ray induced chromosome breakage in the R-bands of human chromosomes.

6. Radiation-induced non-random chromosome breakage.

7. Giemsa technique for the detection of sister chromatid exchanges.

8. Differential Giemsa staining of sister chromatids and the study of chromatid exchanges without autoradiography.

9. Sister chromatid exchange in human chromosomes from normal individuals and patients with ataxia telangiectasia.

10. The incidence of sister chromatid exchanges in cultured human lymphocytes.

1. Sister chromatid exchange points in the heterochromatin and euchromatin regions of Chinese hedgehog chromosomes.

2. Relation between the SCE points and the DNA replication bands.

3. C-bands in chromosomes 1,9, and 16 of twins.

4. Sister chromatid exchanges in cultured peripheral lymphocytes from twins.

Review 5. Genome organization and species formation in vertebrates.

6. Presence of a base line level of sister chromatid exchanges in somatic cells of Drosophila melanogaster in vivo and in vitro.

7. Sister chromatid exchanges and heterochromatin.

Review 8. Sister chromatid exchange (SCE) and structural chromosome aberration in mutagenicity testing.

9. Selective differential staining of sister chromatids of the facultative heterochromatic X chromosome in the female mouse.

10. Sister chromatid exchange in cigarette smokers.