| Literature DB >> 9140189 |
Abstract
We have identified a human gene encoding a protein with 48% amino acid identity to the vaccinia virus (VV) K4L gene product. Both contain motifs characteristic of the phospholipase D (PLD) protein superfamily. These proteins are also related to vaccinia virus p37, encoded by the F13L gene, which is required for envelopment and spread of the virus. The similarity to phospholipase D provides insight into the mechanisms and evolution of these processes.Entities:
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Year: 1997 PMID: 9140189 DOI: 10.1016/s0168-1702(96)01422-0
Source DB: PubMed Journal: Virus Res ISSN: 0168-1702 Impact factor: 3.303