Literature DB >> 9135870

An interactive Web site providing major histocompatibility ligand predictions: application to HIV research.

A S De Groot1, B M Jesdale, E Szu, J R Schafer, R M Chicz, G Deocampo.   

Abstract

EpiMatrix/HIV, a tool that is currently available on the World Wide Web, enables researchers to screen HIV proteins for potential MHC ligands. We have performed a comparison of EpiMatrix predictions to 158 published allotype-specific HLA-associated peptides (MHC ligands) derived from 133 proteins. The top 10 ranked EpiMatrix predictions for each of the 158 HLA allotype-protein pairs were selected for comparison with these published ligands. EpiMatrix correctly identified 134 of 158 published ligands (85%). The algorithm is now available for use by the HIV research community at the URL http:/(/)www.EpiMatrix.com/HIV.

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Year:  1997        PMID： 9135870     DOI： 10.1089/aid.1997.13.529

Source DB:  PubMed          Journal:  AIDS Res Hum Retroviruses        ISSN： 0889-2229            Impact factor:   2.205


  32 in total

1.  Enhancement to the RANKPEP resource for the prediction of peptide binding to MHC molecules using profiles.

Authors:  Pedro A Reche; John-Paul Glutting; Hong Zhang; Ellis L Reinherz
Journal:  Immunogenetics       Date:  2004-09-03       Impact factor: 2.846

2.  HLA-A2-restricted CD8+-cytotoxic-T-cell responses to novel epitopes in Mycobacterium tuberculosis superoxide dismutase, alanine dehydrogenase, and glutamine synthetase.

Authors:  Yuzhi Dong; Sandra Demaria; Xuming Sun; Fabio R Santori; Bill M Jesdale; Anne S De Groot; William N Rom; Yuri Bushkin
Journal:  Infect Immun       Date:  2004-04       Impact factor: 3.441

3.  An Integrated Genomic and Immunoinformatic Approach to H. pylori Vaccine Design.

Authors:  Matthew Ardito; Joanna Fueyo; Ryan Tassone; Frances Terry; Kristen DaSilva; Songhua Zhang; William Martin; Anne S De Groot; Steven F Moss; Leonard Moise
Journal:  Immunome Res       Date:  2011

4.  Identification of immunogenic HLA-B7 "Achilles' heel" epitopes within highly conserved regions of HIV.

Authors:  Anne S De Groot; Daniel S Rivera; Julie A McMurry; Soren Buus; William Martin
Journal:  Vaccine       Date:  2007-12-26       Impact factor: 3.641

Review 5.  Preclinical models used for immunogenicity prediction of therapeutic proteins.

Authors:  Vera Brinks; Daniel Weinbuch; Matthew Baker; Yann Dean; Philippe Stas; Stefan Kostense; Bonita Rup; Wim Jiskoot
Journal:  Pharm Res       Date:  2013-05-07       Impact factor: 4.200

6.  Evaluating Immunogenicity Risk Due to Host Cell Protein Impurities in Antibody-Based Biotherapeutics.

Authors:  Vibha Jawa; Marisa K Joubert; Qingchun Zhang; Meghana Deshpande; Suminda Hapuarachchi; Michael P Hall; Gregory C Flynn
Journal:  AAPS J       Date:  2016-07-22       Impact factor: 4.009

7.  Aspartate-β-hydroxylase induces epitope-specific T cell responses in hepatocellular carcinoma.

Authors:  Yoshito Tomimaru; Sasmita Mishra; Howard Safran; Kevin P Charpentier; William Martin; Anne S De Groot; Stephen H Gregory; Jack R Wands
Journal:  Vaccine       Date:  2015-01-25       Impact factor: 3.641

8.  Coupling sensitive in vitro and in silico techniques to assess cross-reactive CD4(+) T cells against the swine-origin H1N1 influenza virus.

Authors:  Brian C Schanen; Anne S De Groot; L Moise; Matt Ardito; Elizabeth McClaine; William Martin; Vaughan Wittman; William L Warren; Donald R Drake
Journal:  Vaccine       Date:  2011-02-22       Impact factor: 3.641

Review 9.  Coccidioidomycosis: host response and vaccine development.

Authors:  Rebecca A Cox; D Mitchell Magee
Journal:  Clin Microbiol Rev       Date:  2004-10       Impact factor: 26.132

10.  A method for individualizing the prediction of immunogenicity of protein vaccines and biologic therapeutics: individualized T cell epitope measure (iTEM).

Authors:  Tobias Cohen; Leonard Moise; Matthew Ardito; William Martin; Anne S De Groot
Journal:  J Biomed Biotechnol       Date:  2010-07-18
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