Literature DB >> 9135829

The role of cell migration and microchimerism in the induction of tolerance after solid organ transplantation.

R M Jindal1, A Sahota.   

Abstract

A new hypothesis has been proposed which states that microchimerism is the basis for the clinical tolerance seen in long-term survivors of solid organ transplants. Efforts to enhance microchimerism include simultaneous infusion of bone marrow of donor origin and transplantation of a solid organ. Studies are in progress to verify the phenomenon of microchimerism and its role in clinical tolerance.

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Year:  1997        PMID: 9135829      PMCID: PMC2431236          DOI: 10.1136/pgmj.73.857.146

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN: 0032-5473            Impact factor:   2.401


  35 in total

1.  Actively acquired tolerance of foreign cells.

Authors:  R E BILLINGHAM; L BRENT; P B MEDAWAR
Journal:  Nature       Date:  1953-10-03       Impact factor: 49.962

Review 2.  The role of graft-derived dendritic leukocytes in the rejection of vascularized organ allografts. Recent findings on the migration and function of dendritic leukocytes after transplantation.

Authors:  C P Larsen; J M Austyn; P J Morris
Journal:  Ann Surg       Date:  1990-09       Impact factor: 12.969

3.  Macrophage migration into hepatic xenografts in the hamster-to-rat combination.

Authors:  Y Yamaguchi; E C Halperin; K Mori; M Misumi; T Katsumori; N Takata; M Goto; Y Makino; N Kikuchi; K Takahashi
Journal:  Transplant Proc       Date:  1991-02       Impact factor: 1.066

4.  Reduction of the in vitro cytotoxic lymphocyte response produced by in vivo exposure to semiallogeneic cells: recruitment or active suppression?

Authors:  R G Miller; R A Phillips
Journal:  J Immunol       Date:  1976-11       Impact factor: 5.422

5.  IL-4 directs the development of Th2-like helper effectors.

Authors:  S L Swain; A D Weinberg; M English; G Huston
Journal:  J Immunol       Date:  1990-12-01       Impact factor: 5.422

Review 6.  Post transplantation donor-specific bone marrow transfusion in polyclonal antilymphocyte serum-treated recipients: the optimal cellular antigen for induction of unresponsiveness to organ allografts.

Authors:  A P Monaco; M L Wood; T Maki; J J Gozzo
Journal:  Transplant Proc       Date:  1988-12       Impact factor: 1.066

7.  Induction of transplantation tolerance by intravenous injection of allogeneic lymphocytes across an H-2 class II mismatch. Different mechanisms operate in tolerization across an H-2 class I vs. H-2 class II disparity.

Authors:  E van Twuyver; W M Kast; R J Mooijaart; C J Melief; L P De Waal
Journal:  Eur J Immunol       Date:  1990-02       Impact factor: 5.532

8.  Severe graft-versus-host disease in a liver-transplant recipient.

Authors:  J F Burdick; G B Vogelsang; W J Smith; E R Farmer; W B Bias; S H Kaufmann; J Horn; P M Colombani; H A Pitt; B A Perler
Journal:  N Engl J Med       Date:  1988-03-17       Impact factor: 91.245

9.  Abundant class of human DNA polymorphisms which can be typed using the polymerase chain reaction.

Authors:  J L Weber; P E May
Journal:  Am J Hum Genet       Date:  1989-03       Impact factor: 11.025

10.  Use of cryopreserved donor bone marrow in cadaver kidney allograft recipients.

Authors:  W H Barber; A G Diethelm; D A Laskow; M H Deierhoi; B A Julian; J J Curtis
Journal:  Transplantation       Date:  1989-01       Impact factor: 4.939

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  1 in total

Review 1.  Post-transplant diabetes mellitus. The role of immunosuppression.

Authors:  R M Jindal; R A Sidner; M L Milgrom
Journal:  Drug Saf       Date:  1997-04       Impact factor: 5.606

  1 in total

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