Literature DB >> 9134997

Identification of a 790-kilobase region of common allelic loss in chromosome 10q25-q26 in human endometrial cancer.

S Nagase1, H Yamakawa, S Sato, A Yajima, A Horii.   

Abstract

We previously identified two commonly deleted regions on chromosome bands 10q25-q26 in endometrial cancer: an 8-cM region and a 12-cM region. In the present study, we further studied the 8-cM region with 83 endometrial cancer specimens and 14 microsatellite markers and narrowed it down to a 1-cM region between D10S587 and D10S1723. This result was confirmed by two-color fluorescence in situ hybridization analysis. An association between histopathologically lower grade tumor and allelic loss (P = 0.03 by Fisher's exact test) was also observed. We also constructed a yeast artificial chromosome (YAC) contig and found that one YAC clone, which was 790 kb in size, harbored the whole 1-cM region of common allelic loss.

Entities:  

Mesh：

Substances：

Year:  1997        PMID： 9134997

Source DB:  PubMed          Journal:  Cancer Res        ISSN： 0008-5472            Impact factor:   12.701


  8 in total

1.  Genomic analysis of the thymine-DNA glycosylase (TDG) gene on 12q22-q24.1 in human pancreatic ductal adenocarcinoma.

Authors:  T Yatsuoka; T Furukawa; T Abe; T Yokoyama; M Sunamura; M Kobari; S Matsuno; A Horii
Journal:  Int J Pancreatol       Date:  1999-04

2.  Cell-autonomous activation of the PI3-kinase pathway initiates endometrial cancer from adult uterine epithelium.

Authors:  Sanaz Memarzadeh; Yang Zong; Deanna M Janzen; Andrew S Goldstein; Donghui Cheng; Takeshi Kurita; Amanda M Schafenacker; Jiaoti Huang; Owen N Witte
Journal:  Proc Natl Acad Sci U S A       Date:  2010-09-20       Impact factor: 11.205

Review 3.  High-intermediate risk endometrial cancer: moving toward a molecularly based risk assessment profile.

Authors:  Tavonna D Kako; Maahum Z Kamal; Jhalak Dholakia; Carly B Scalise; Rebecca C Arend
Journal:  Int J Clin Oncol       Date:  2022-01-17       Impact factor: 3.402

4.  FATS is a transcriptional target of p53 and associated with antitumor activity.

Authors:  Xifeng Zhang; Qian Zhang; Jun Zhang; Li Qiu; Shuang-Shuang Yan; Juling Feng; Yan Sun; Xingxu Huang; Karen H Lu; Zheng Li
Journal:  Mol Cancer       Date:  2010-09-16       Impact factor: 27.401

5.  soc-2 encodes a leucine-rich repeat protein implicated in fibroblast growth factor receptor signaling.

Authors:  L M Selfors; J L Schutzman; C Z Borland; M J Stern
Journal:  Proc Natl Acad Sci U S A       Date:  1998-06-09       Impact factor: 11.205

6.  Detailed deletion mapping of chromosome band 14q32 in human neuroblastoma defines a 1.1-Mb region of common allelic loss.

Authors:  M Hoshi; N Otagiri; H O Shiwaku; S Asakawa; N Shimizu; Y Kaneko; R Ohi; Y Hayashi; A Horii
Journal:  Br J Cancer       Date:  2000-06       Impact factor: 7.640

Review 7.  Common fragile sites: genomic hotspots of DNA damage and carcinogenesis.

Authors:  Ke Ma; Li Qiu; Kristin Mrasek; Jun Zhang; Thomas Liehr; Luciana Gonçalves Quintana; Zheng Li
Journal:  Int J Mol Sci       Date:  2012-09-20       Impact factor: 6.208

8.  The PTEN, BAX, and IGFIIR genes are mutated in endometrial atypical hyperplasia.

Authors:  K Yoshinaga; H Sasano; T Furukawa; H Yamakawa; M Yuki; S Sato; A Yajima; A Horii
Journal:  Jpn J Cancer Res       Date:  1998-10
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.