Literature DB >> 9134745

Selective cytotoxicity of ginkgetin from Selaginella moellendorffii.

C M Sun1, W J Syu, Y T Huang, C C Chen, J C Ou.   

Abstract

Bioassay-directed fractionation of an ethanolic extract of Selaginella moellendorffii has led to the isolation of a known biflavone, ginkgetin (1). A dose-dependent inhibition was observed with 1 on the growth of OVCAR-3 (human ovarian adenocarcinoma) cells with 50% inhibition occurring at 1.8 micrograms/mL. Nonbioactive fractions yielded four additional known biflavones, amentoflavone 7,4',7",4"'-tetramethyl ether, kayaflavone, podocarpusflavone A, and amentoflavone.

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Year:  1997        PMID： 9134745     DOI： 10.1021/np960608e

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  11 in total

1.  Indian herb 'Sanjeevani' (Selaginella bryopteris) can promote growth and protect against heat shock and apoptotic activities of ultra violet and oxidative stress.

Authors:  Nand K Sah; Shyam Nandan P Singh; Sudhir Sahdev; Sharmishta Banerji; Vidyanath Jha; Zakir Khan; Seyed E Hasnain
Journal:  J Biosci       Date:  2005-09       Impact factor: 1.826

Review 2.  A review of the use of pteridophytes for treating human ailments.

Authors:  Xavier-Ravi Baskaran; Antony-Varuvel Geo Vigila; Shou-Zhou Zhang; Shi-Xiu Feng; Wen-Bo Liao
Journal:  J Zhejiang Univ Sci B       Date:  2018 Feb.       Impact factor: 3.066

3.  Effects of Ginkgo biloba extract on cell proliferation and cytotoxicity in human hepatocellular carcinoma cells.

Authors:  Jane C J Chao; Chia Chou Chu
Journal:  World J Gastroenterol       Date:  2004-01       Impact factor: 5.742

4.  Anti-tumor effect of ginkgetin on human hepatocellular carcinoma cell lines by inducing cell cycle arrest and promoting cell apoptosis.

Authors:  Qiong Liu; Lingying Chen; Wenjun Yin; Yuehua Nie; Penghui Zeng; Xin Yang
Journal:  Cell Cycle       Date:  2021-12-08       Impact factor: 4.534

5.  Comparison of cytotoxic activities of extracts from Selaginella species.

Authors:  Juan Li; Xiang Lei; Ke-Li Chen
Journal:  Pharmacogn Mag       Date:  2014-10       Impact factor: 1.085

6.  In vivo antileishmanial activity and chemical profile of polar extract from Selaginella sellowii.

Authors:  Dayane Priscilla de Souza Queiroz; Carlos Alexandre Carollo; Mônica Cristina Toffoli Kadri; Yasmin Silva Rizk; Vanessa Carneiro Pereira de Araujo; Paulo Eduardo de Oliveira Monteiro; Patrik Oening Rodrigues; Elisa Teruya Oshiro; Maria de Fátima Cepa Matos; Carla Cardozo Pinto de Arruda
Journal:  Mem Inst Oswaldo Cruz       Date:  2016-02-19       Impact factor: 2.743

Review 7.  A Review on the Phytochemistry, Pharmacology, and Pharmacokinetics of Amentoflavone, a Naturally-Occurring Biflavonoid.

Authors:  Sheng Yu; Hui Yan; Li Zhang; Mingqiu Shan; Peidong Chen; Anwei Ding; Sam Fong Yau Li
Journal:  Molecules       Date:  2017-02-16       Impact factor: 4.411

8.  Deciphering the Molecular Mechanism Responsible for Efficiently Inhibiting Metastasis of Human Non-Small Cell Lung and Colorectal Cancer Cells Targeting the Matrix Metalloproteinases by Selaginella repanda.

Authors:  Mohd Adnan; Arif Jamal Siddiqui; Walid Sabri Hamadou; Mejdi Snoussi; Riadh Badraoui; Syed Amir Ashraf; Arshad Jamal; Amir Mahgoub Awadelkareem; Manojkumar Sachidanandan; Sibte Hadi; Mushtaq Ahmad Khan; Mitesh Patel
Journal:  Plants (Basel)       Date:  2021-05-14

9.  Chemodiversity in Selaginella: a reference system for parallel and convergent metabolic evolution in terrestrial plants.

Authors:  Jing-Ke Weng; Joseph P Noel
Journal:  Front Plant Sci       Date:  2013-05-10       Impact factor: 5.753

10.  Antiviral Activity of Total Flavonoid Extracts from Selaginella moellendorffii Hieron against Coxsackie Virus B3 In Vitro and In Vivo.

Authors:  Dan Yin; Juan Li; Xiang Lei; Yimei Liu; Zhanqiu Yang; Keli Chen
Journal:  Evid Based Complement Alternat Med       Date:  2014-05-19       Impact factor: 2.629
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