| Literature DB >> 9134116 |
T Momose1, J Nishikawa, T Watanabe, Y Sasaki, M Senda, K Kubota, Y Sato, M Funakoshi, S Minakuchi.
Abstract
The interaction between mastication and cerebral blood flow was studied in 12 healthy volunteers (five males and seven females) aged 18-40 years. Positron-emission tomography (PET) autoradiography was carried out after bolus injection of 1.5 GBq H₂¹⁵O (¹⁵O-labelled water) with a half life of 2 min. The PET images were superimposed on magnetic resonance images of each participant. The regional cerebral blood flow images were normalized by the global cerebral blood flow value, and subtraction images (those during gum-chewing minus those during resting) were created and recut at the magnetic resonance image slice positions. Gum specially designed for chewing training was used. Mastication increased regional cerebral blood flow in the primary sensorimotor areas by 25-28%, in the supplementary motor areas and insulae by 9-17%, and in the cerebellum and striatum by 8-11%. These increases demonstrate that chewing activates widespread regions of the brain.Entities:
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Year: 1997 PMID： 9134116 DOI： 10.1016/s0003-9969(96)00081-7
Source DB: PubMed Journal: Arch Oral Biol ISSN： 0003-9969 Impact factor: 2.633