| Literature DB >> 9132175 |
F Takano1, Y Kikuchi, S Fushiya, H Hojo, S Nozoe, N Yahagi, R Yahagi, Y Kondo.
Abstract
Isaria japonica YASUDA was cultured in a liquid medium, and its culture fluid (IJCE) was tested for stimulatory activity to humoral antibody production. IJCE significantly enhanced the production of anti-sheep red blood cell (SRBC) plaque forming cells (PFC) by oral ingestions at 10 and 30 mg/kg/d for 4 consecutive days, either before or after SRBC challenge. It also recovered the reduction of anti-SRBC PFC response and number of spleen cells caused by treatment with 5-fluorouracil. It is suggested that IJCE is a promising source for an immunomodulating tool or medicine.Entities:
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Year: 1996 PMID： 9132175 DOI： 10.1248/bpb.19.641
Source DB: PubMed Journal: Biol Pharm Bull ISSN： 0918-6158 Impact factor: 2.233