Literature DB >> 9131785

Two limonoids from Turraea obtusifolia (Meliaceae), prieurianin and rohitukin, antagonise 20-hydroxyecdysone action in a Drosophila cell line.

S D Sarker1, T Savchenko, P Whiting, V Sik, L Dinan.   

Abstract

Bioassay-assisted HPLC analyses yielded two prieurianin-type limonoids, prieurianin and rohitukin, from the seeds of Turraea obtusifolia, which act as antagonists of 20-hydroxyecdysone action in the Drosophila melanogaster BII cell line. With a 20-hydroxyecdysone concentration of 5 x 10(-8) M, the ED50 values for prieurianin and rohitukin are 10(-5) M and 1.25 x 10(-4) M, respectively.

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Year:  1997        PMID: 9131785     DOI: 10.1002/(SICI)1520-6327(1997)35:1/2<211::AID-ARCH19>3.0.CO;2-E

Source DB:  PubMed          Journal:  Arch Insect Biochem Physiol        ISSN: 0739-4462            Impact factor:   1.698


  6 in total

1.  Prieurianin Causes Weight Loss in Diet-Induced Obese Mice and Inhibits Adipogenesis in Cultured Preadipocytes.

Authors:  Ahmed Kablan; Rudel A Saunders; Maria Szkudlarek-Mikho; Andrew J B Chin; Raul M Bosio; Kazuyuki Fujii; Joseph Shapiro; Khew-Voon Chin
Journal:  J Diabetes Metab       Date:  2010-09-29

Review 2.  Insecticidal Triterpenes in Meliaceae: Plant Species, Molecules, and Activities: Part II (Cipadessa, Melia).

Authors:  Meihong Lin; Xiaoyang Bi; Lijuan Zhou; Jiguang Huang
Journal:  Int J Mol Sci       Date:  2022-05-10       Impact factor: 6.208

3.  Endosidin1 defines a compartment involved in endocytosis of the brassinosteroid receptor BRI1 and the auxin transporters PIN2 and AUX1.

Authors:  Stéphanie Robert; S Narasimha Chary; Georgia Drakakaki; Shundai Li; Zhenbiao Yang; Natasha V Raikhel; Glenn R Hicks
Journal:  Proc Natl Acad Sci U S A       Date:  2008-06-11       Impact factor: 11.205

4.  Synthesis of the B-seco limonoid core scaffold.

Authors:  Hanna Bruss; Hannah Schuster; Rémi Martinez; Markus Kaiser; Andrey P Antonchick; Herbert Waldmann
Journal:  Beilstein J Org Chem       Date:  2014-01-16       Impact factor: 2.883

5.  Antiplasmodial and cytotoxic activities of the constituents of Turraea robusta and Turraea nilotica.

Authors:  Beatrice N Irungu; Nicholas Adipo; Jennifer A Orwa; Francis Kimani; Matthias Heydenreich; Jacob O Midiwo; Per Martin Björemark; Mikael Håkansson; Abiy Yenesew; Máté Erdélyi
Journal:  J Ethnopharmacol       Date:  2015-08-28       Impact factor: 4.360

6.  Nitrogen-containing dimeric nor-multiflorane triterpene from a Turraea sp.

Authors:  Vincent E Rasamison; L Harinantenaina Rakotondraibe; Carla Slebodnick; Peggy J Brodie; Michel Ratsimbason; Karen TenDyke; Yongchun Shen; Lucien M Randrianjanaka; David G I Kingston
Journal:  Org Lett       Date:  2014-04-28       Impact factor: 6.005

  6 in total

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