Literature DB >> 913022

Tolerance to marijuana: heart rate and subjective "high".

R Nowlan, S Cohen.   

Abstract

In a 94-day supervised study of 30 subjects smoking marijuana, with drug-free periods interspersed, mean heart rate and subjective "high" decreased over the smoking period. Light smokers had greater chronotrophic and subjective effects than heavy smokers, but both demonstrated evidence of tolerance. Cumulation and minor withdrawal effects were noted.

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Year:  1977        PMID： 913022     DOI： 10.1002/cpt1977225part1550

Source DB:  PubMed          Journal:  Clin Pharmacol Ther        ISSN： 0009-9236            Impact factor:   6.875


  14 in total

1.  Tolerance to, and symmetrical cross-tolerance between, cannabinol and delta 9-tetrahydrocannabinol.

Authors:  B S Fish; P Consroe
Journal:  Experientia       Date:  1981-03-15

Review 2.  Marijuana dependence: not just smoke and mirrors.

Authors:  Divya Ramesh; Joel E Schlosburg; Jason M Wiebelhaus; Aron H Lichtman
Journal:  ILAR J       Date:  2011

Review 3.  Cannabinoids and Epilepsy.

Authors:  Evan C Rosenberg; Richard W Tsien; Benjamin J Whalley; Orrin Devinsky
Journal:  Neurotherapeutics       Date:  2015-10       Impact factor: 7.620

Review 4.  Cannabis reinforcement and dependence: role of the cannabinoid CB1 receptor.

Authors:  Ziva D Cooper; Margaret Haney
Journal:  Addict Biol       Date:  2008-02-14       Impact factor: 4.280

5.  Relief of cannabis withdrawal symptoms and cannabis quitting strategies in people with schizophrenia.

Authors:  Maju Mathew Koola; Douglas Lee Boggs; Deanna Lynn Kelly; Fang Liu; Jared Allen Linthicum; Hailey Elaine Turner; Robert Patrick McMahon; David Alan Gorelick
Journal:  Psychiatry Res       Date:  2013-08-20       Impact factor: 3.222

6.  Cannabis withdrawal in chronic, frequent cannabis smokers during sustained abstinence within a closed residential environment.

Authors:  Dayong Lee; Jennifer R Schroeder; Erin L Karschner; Robert S Goodwin; Jussi Hirvonen; David A Gorelick; Marilyn A Huestis
Journal:  Am J Addict       Date:  2014 May-Jun

7.  Cannabis withdrawal in the United States: results from NESARC.

Authors:  Deborah S Hasin; Katherine M Keyes; Donald Alderson; Shuang Wang; Efrat Aharonovich; Bridget F Grant
Journal:  J Clin Psychiatry       Date:  2008-09-09       Impact factor: 4.384

Review 8.  Cannabinoids: reward, dependence, and underlying neurochemical mechanisms--a review of recent preclinical data.

Authors:  Gianluigi Tanda; Steven R Goldberg
Journal:  Psychopharmacology (Berl)       Date:  2003-06-24       Impact factor: 4.530

Review 9.  Actions of delta-9-tetrahydrocannabinol in cannabis: relation to use, abuse, dependence.

Authors:  Ziva D Cooper; Margaret Haney
Journal:  Int Rev Psychiatry       Date:  2009-04

10.  Relationship between plasma delta-9-tetrahydrocannabinol concentration and pharmacologic effects in man.

Authors:  D M Cocchetto; S M Owens; M Perez-Reyes; S DiGuiseppi; L L Miller
Journal:  Psychopharmacology (Berl)       Date:  1981       Impact factor: 4.530
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