Literature DB >> 9130044

The human cytomegalovirus major immediate-early gene.

R M Stenberg1.   

Abstract

Immediate-early genes function to regulate viral and cellular gene expression during the course of virus replication. The major immediate-early gene region of human cytomegalovirus plays a key role in affecting activation and repression of viral and cellular genes. These proteins intimately associate and/or interact with viral and cellular proteins during this process. Herein, we will discuss the current understanding of this complex gene region.

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Year:  1996        PMID： 9130044     DOI： 10.1159/000150505

Source DB:  PubMed          Journal:  Intervirology        ISSN： 0300-5526            Impact factor:   1.763


  47 in total

1.  A strong negative transcriptional regulatory region between the human cytomegalovirus UL127 gene and the major immediate-early enhancer.

Authors:  C A Lundquist; J L Meier; M F Stinski
Journal:  J Virol       Date:  1999-11       Impact factor: 5.103

2.  Random, asynchronous, and asymmetric transcriptional activity of enhancer-flanking major immediate-early genes ie1/3 and ie2 during murine cytomegalovirus latency in the lungs.

Authors:  N K Grzimek; D Dreis; S Schmalz; M J Reddehase
Journal:  J Virol       Date:  2001-03       Impact factor: 5.103

3.  In vivo replication of recombinant murine cytomegalovirus driven by the paralogous major immediate-early promoter-enhancer of human cytomegalovirus.

Authors:  N K Grzimek; J Podlech; H P Steffens; R Holtappels; S Schmalz; M J Reddehase
Journal:  J Virol       Date:  1999-06       Impact factor: 5.103

4.  The major immediate-early gene ie3 of mouse cytomegalovirus is essential for viral growth.

Authors:  A Angulo; P Ghazal; M Messerle
Journal:  J Virol       Date:  2000-12       Impact factor: 5.103

5.  The human cytomegalovirus major immediate-early enhancer determines the efficiency of immediate-early gene transcription and viral replication in permissive cells at low multiplicity of infection.

Authors:  Hiroki Isomura; Mark F Stinski
Journal:  J Virol       Date:  2003-03       Impact factor: 5.103

6.  Role of the proximal enhancer of the major immediate-early promoter in human cytomegalovirus replication.

Authors:  Hiroki Isomura; Tatsuya Tsurumi; Mark F Stinski
Journal:  J Virol       Date:  2004-12       Impact factor: 5.103

7.  A short cis-acting motif in the M112-113 promoter region is essential for IE3 to activate M112-113 gene expression and is important for murine cytomegalovirus replication.

Authors:  Kareni J Perez; Francisco Puerta Martínez; Ruth Cosme-Cruz; Neysa M Perez-Crespo; Qiyi Tang
Journal:  J Virol       Date:  2012-12-19       Impact factor: 5.103

8.  Roles of polypyrimidine tract binding proteins in major immediate-early gene expression and viral replication of human cytomegalovirus.

Authors:  Ruth S Cruz Cosme; Yasuhiro Yamamura; Qiyi Tang
Journal:  J Virol       Date:  2009-01-14       Impact factor: 5.103

9.  Analysis of splice variants of the immediate-early 1 region of human cytomegalovirus.

Authors:  Sita Awasthi; Jennifer A Isler; James C Alwine
Journal:  J Virol       Date:  2004-08       Impact factor: 5.103

10.  Characterization of the transcriptional repressive element of the human cytomegalovirus immediate-early US3 gene.

Authors:  B J Biegalke
Journal:  J Virol       Date:  1998-07       Impact factor: 5.103
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