Literature DB >> 9129198

Epitope mapping: a new method for biological evaluation and immunotoxicology.

J M Saint-Remy1.   

Abstract

The extraordinary capacity of the immune system to recognise and distinguish between molecules that are almost identical can be exploited to generate reagents useful for the identification of specific determinants on drugs, blood-derived products, hormones, receptors or micro-organisms. This manuscript provides a rationale for the use of epitope mapping and a brief outline of its multiple applications.

Mesh:

Year:  1997        PMID: 9129198     DOI: 10.1016/s0300-483x(96)03599-8

Source DB:  PubMed          Journal:  Toxicology        ISSN: 0300-483X            Impact factor:   4.221


  3 in total

1.  Epitope mapping of a monoclonal antibody against human thrombin by H/D-exchange mass spectrometry reveals selection of a diverse sequence in a highly conserved protein.

Authors:  Abel Baerga-Ortiz; Carrie A Hughes; Jeffrey G Mandell; Elizabeth A Komives
Journal:  Protein Sci       Date:  2002-06       Impact factor: 6.725

2.  Mapping the Energetic Epitope of an Antibody/Interleukin-23 Interaction with Hydrogen/Deuterium Exchange, Fast Photochemical Oxidation of Proteins Mass Spectrometry, and Alanine Shave Mutagenesis.

Authors:  Jing Li; Hui Wei; Stanley R Krystek; Derek Bond; Ty M Brender; Daniel Cohen; Jena Feiner; Nels Hamacher; Johanna Harshman; Richard Y-C Huang; Susan H Julien; Zheng Lin; Kristina Moore; Luciano Mueller; Claire Noriega; Preeti Sejwal; Paul Sheppard; Brenda Stevens; Guodong Chen; Adrienne A Tymiak; Michael L Gross; Lumelle A Schneeweis
Journal:  Anal Chem       Date:  2017-02-09       Impact factor: 6.986

3.  Crystal structure of an antiviral ankyrin targeting the HIV-1 capsid and molecular modeling of the ankyrin-capsid complex.

Authors:  Warachai Praditwongwan; Phimonphan Chuankhayan; Somphot Saoin; Tanchanok Wisitponchai; Vannajan Sanghiran Lee; Sawitree Nangola; Saw See Hong; Philippe Minard; Pierre Boulanger; Chun-Jung Chen; Chatchai Tayapiwatana
Journal:  J Comput Aided Mol Des       Date:  2014-07-05       Impact factor: 3.686

  3 in total

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