| Literature DB >> 912650 |
Abstract
Levels of glycoprotein:sialyltransferase activity (EC 2.4.99.1; CMP-acetyl-neuraminate:D-galactosyl-glycoprotein N-acetylneuraminyl-transferase) were measured in plasma of patients with neoplastic disease, and were found elevated above normal control values in 85% of patients examined. There was a correlation between enzyme levels and course of disea-e in 46 of 57 patients studied serially during therapy. Plasma sialyltransferase may be a useful marker enzyme for monitoring effectiveness of therapeutic programs for disseminated neoplasms.Entities:
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Year: 1977 PMID: 912650 DOI: 10.1002/1097-0142(197703)39:3<1129::aid-cncr2820390318>3.0.co;2-3
Source DB: PubMed Journal: Cancer ISSN: 0008-543X Impact factor: 6.860