Literature DB >> 912650

Alterations in plasma sialyltransferase levels in patients with neoplastic disease.

M Henderson, D Kessel.   

Abstract

Levels of glycoprotein:sialyltransferase activity (EC 2.4.99.1; CMP-acetyl-neuraminate:D-galactosyl-glycoprotein N-acetylneuraminyl-transferase) were measured in plasma of patients with neoplastic disease, and were found elevated above normal control values in 85% of patients examined. There was a correlation between enzyme levels and course of disea-e in 46 of 57 patients studied serially during therapy. Plasma sialyltransferase may be a useful marker enzyme for monitoring effectiveness of therapeutic programs for disseminated neoplasms.

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Year:  1977        PMID: 912650     DOI: 10.1002/1097-0142(197703)39:3<1129::aid-cncr2820390318>3.0.co;2-3

Source DB:  PubMed          Journal:  Cancer        ISSN: 0008-543X            Impact factor:   6.860


  10 in total

1.  [Glycoproteins: their biological and clinical significance. II (author's transl)].

Authors:  E Köttgen; C Bauer; W Reutter; W Gerok
Journal:  Klin Wochenschr       Date:  1979-03-01

Review 2.  Serum sialylation changes in cancer.

Authors:  Zejian Zhang; Manfred Wuhrer; Stephanie Holst
Journal:  Glycoconj J       Date:  2018-04-21       Impact factor: 2.916

3.  Post-operative serum sialyltransferase levels and prognosis in breast cancer.

Authors:  J Stewart; R Rubens; R Millis; J Hayward; S Hoare; R Bulbrook; D Kessel
Journal:  Breast Cancer Res Treat       Date:  1983       Impact factor: 4.872

Review 4.  Serum-sialyltransferase activity in cancer patients.

Authors:  P G Berge; A Wilhelm; H Schriewer; G Wüst
Journal:  Klin Wochenschr       Date:  1982-05-03

5.  Sialyltransferase activity in tumor tissues.

Authors:  P G Berge; A Wilhelm; H Schriewer
Journal:  Klin Wochenschr       Date:  1984-04-02

6.  Dolichol-bound oligosaccharides and the transfer of distal monosaccharides in the synthesis of glycoproteins by normal and tumor mammary epithelial cells.

Authors:  A J Parodi; E W Blank; J A Peterson; R L Ceriani
Journal:  Breast Cancer Res Treat       Date:  1982       Impact factor: 4.872

7.  Elevated glycosyltransferase activities in infected or traumatized hosts: nonspecific response to inflammation.

Authors:  P G Canonico; J S Little; M C Powanda; K A Bostian; W R Beisel
Journal:  Infect Immun       Date:  1980-07       Impact factor: 3.441

8.  Sialyltransferase levels and sialic acid concentrations in sera of patients with malignant melanomas.

Authors:  W P Herrmann; W Gielen
Journal:  Arch Dermatol Res       Date:  1979-07-30       Impact factor: 3.017

9.  Serum sialyl transferase levels in patients with metastatic breast cancer treated by chemotherapy.

Authors:  J F Stewart; R D Rubens; S Hoare; R D Bulbrook; D Kessel
Journal:  Br J Cancer       Date:  1982-08       Impact factor: 7.640

Review 10.  Sialylation is involved in cell fate decision during development, reprogramming and cancer progression.

Authors:  Fenjie Li; Junjun Ding
Journal:  Protein Cell       Date:  2018-11-26       Impact factor: 14.870

  10 in total

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