OBJECTIVES: This study is designed to estimate the prostate cancer-specific mortality according to patient age and tumor grade in an unselected population of patients with prostate cancer who mostly received deferred or direct hormonal treatment as initial treatment. METHODS: The study population was composed of 6514 patients diagnosed with prostate cancer during 1971 to 1987 in northern Sweden. For those who died during follow-up, the cause of death was determined from the comprehensive Swedish registry data (population registries and causes of death registry). RESULTS: About 85% of these patients died during the 7 to 23 years of follow-up, and the prostate cancer-specific mortality was estimated to be 55%. Age at diagnosis was found to be a strong predictor of prostate cancer death. Patients diagnosed before the age of 60 had an 80% risk of dying of prostate cancer, whereas those over 80 years of age at diagnosis had less than a 50% risk of prostate cancer-related death. CONCLUSIONS: The prostate cancer mortality is high but decreases with older age at diagnosis. We found, using data from the causes of death registry, that the relative survival and the cause-specific survival of these patients were compatible with each other.
OBJECTIVES: This study is designed to estimate the prostate cancer-specific mortality according to patient age and tumor grade in an unselected population of patients with prostate cancer who mostly received deferred or direct hormonal treatment as initial treatment. METHODS: The study population was composed of 6514 patients diagnosed with prostate cancer during 1971 to 1987 in northern Sweden. For those who died during follow-up, the cause of death was determined from the comprehensive Swedish registry data (population registries and causes of death registry). RESULTS: About 85% of these patients died during the 7 to 23 years of follow-up, and the prostate cancer-specific mortality was estimated to be 55%. Age at diagnosis was found to be a strong predictor of prostate cancer death. Patients diagnosed before the age of 60 had an 80% risk of dying of prostate cancer, whereas those over 80 years of age at diagnosis had less than a 50% risk of prostate cancer-related death. CONCLUSIONS: The prostate cancer mortality is high but decreases with older age at diagnosis. We found, using data from the causes of death registry, that the relative survival and the cause-specific survival of these patients were compatible with each other.
Authors: Jonathan L Wright; Erika M Kwon; Daniel W Lin; Suzanne Kolb; Joseph S Koopmeiners; Ziding Feng; Elaine A Ostrander; Janet L Stanford Journal: Prostate Date: 2010-07-01 Impact factor: 4.104
Authors: N J Kinnear; G Kichenadasse; S Plagakis; M E O'Callaghan; T Kopsaftis; S Walsh; D Foreman Journal: World J Urol Date: 2016-04-12 Impact factor: 4.226