| Literature DB >> 912324 |
A Horsman, J C Gallagher, M Simpson, B E Nordin.
Abstract
In a prospective trial in 72 postmenopausal women to compare the effects on bone loss of no treatment, treatment with oestrogen, and treatment with calcium the women were followed up for at least two years and examined densitometrically and morphometrically. Women in the untreated control group continued to lose bone during the two years, whereas the oestrogen-treated group lost none. Loss in the calcium-treated group was intermediate. Oestrogen appeared to inhibit endosteal bone resorption and may have stimulated subperiosteal bone apposition.Entities:
Keywords: Clinical Research; Comparative Studies; Contraception; Contraceptive Agents, Estrogen--administraction and dosage; Contraceptive Agents, Estrogen--therapeutic use; Contraceptive Agents, Female--administraction and dosage; Contraceptive Agents, Female--therapeutic use; Contraceptive Agents--administraction and dosage; Contraceptive Agents--therapeutic use; Ethinyl Estradiol--administraction and dosage; Ethinyl Estradiol--therapeutic use; Family Planning; Menopause; Prospective Studies; Reproduction; Research Methodology; Studies
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Year: 1977 PMID： 912324 PMCID： PMC1631969 DOI： 10.1136/bmj.2.6090.789
Source DB: PubMed Journal: Br Med J ISSN： 0007-1447