Literature DB >> 9118707

Early complications and value of initial clinical and paraclinical observations in victims of smoke inhalation without burns.

P Hantson1, R Butera, J L Clemessy, A Michel, F J Baud.   

Abstract

OBJECTIVE: To evaluate the incidence of early pulmonary complications and the value of initial clinical signs and paraclinical investigations in victims of smoke inhalation not suffering from burns following structural fires.
DESIGN: Retrospective chart review.
SETTING: Thirteen-bed ICU. PATIENTS: Sixty-four victims of smoke inhalation following household fires were admitted to the ICU between January 1987 and December 1992. Exclusion criteria from the study were patients with cutaneous burns or multiple trauma or blast injury, and patients found in cardiac arrest.
METHODS: Clinical, biological, and radiologic parameters were collected over a 5-day period.
RESULTS: The mortality rate in relation to progressive respiratory failure was 3.1%. Mean ICU stay was 5.8 days (range, 1 to 33 days), and was longer in the patients presenting with soot deposits in the oropharynx (p = 0.02), dysphonia (D) (p = 0.05), or ronchi (R) (p = 0.0004) at the first examination, and in those having a positive sputum bacteriologic analysis (p = 0.003) or requiring parenteral bronchodilator agents for more than 24 h (p = 0.04). Thirty-five patients underwent mechanical ventilation (MV) for a mean of 101.2 h (range, 8 to 648 h). Mean MV duration was higher in the patients presenting initially with R (p = 0.003), high carbon monoxide (but not cyanide) levels (p = 0.02), or a positive bacteriologic sample (p = 0.0001). Positive bacteriologic sampling correlated with the presence of D (p = 0.02) or R (p = 0.04) and with immediate intubation (p = 0.0003). No correlation was found with chest radiograph.
CONCLUSIONS: In this selected series of fire victims without cutaneous burns, respiratory injury was frequent. The initial clinical signs may be helpful to predict pulmonary complications.

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Year:  1997        PMID: 9118707     DOI: 10.1378/chest.111.3.671

Source DB:  PubMed          Journal:  Chest        ISSN: 0012-3692            Impact factor:   9.410


  5 in total

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Authors:  Johanna M Gretarsdottir; Ian H Lambert; Stefan Sturup; Sigridur G Suman
Journal:  ACS Pharmacol Transl Sci       Date:  2022-09-09

2.  Pediatric upper aero-digestive and respiratory tract burns.

Authors:  Adam Ofri; John G Harvey; Andrew J A Holland
Journal:  Int J Burns Trauma       Date:  2013-11-01

Review 3.  The Toxicological Mechanisms of Environmental Soot (Black Carbon) and Carbon Black: Focus on Oxidative Stress and Inflammatory Pathways.

Authors:  Rituraj Niranjan; Ashwani Kumar Thakur
Journal:  Front Immunol       Date:  2017-06-30       Impact factor: 7.561

4.  Isolated inhalational injury: Clinical course and outcomes in a multidisciplinary intensive care unit.

Authors:  Jose Chacko; Nikahat Jahan; Gagan Brar; Ramanathan Moorthy
Journal:  Indian J Crit Care Med       Date:  2012-04

5.  Smoke inhalation lung injury: an update.

Authors:  Robert H Demling
Journal:  Eplasty       Date:  2008-05-16
  5 in total

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