Literature DB >> 9118003

Lysosomal membrane stabilization by alpha-tocopherol against the damaging action of Vipera russelli venom phospholipase A2.

A K Mukherjee1, S K Ghosal, C R Maity.   

Abstract

This investigation shows the membrane stabilizing effect of alpha-tocopherol against the damaging action of viper venom phospholipase A2 (PLA2). Liver lysosomal membranes from rats fed 100 mg and 200 mg alpha-tocopherol acetate per kilogram of diet were more resistant to damage by viper venom PLA2 compared with vitamin E-deficient rats. The membrane stabilizing effect of vitamin E is proposed to be due to the formation of a complex with the phospholipid hydrolysis products of the membrane.

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Year:  1997        PMID: 9118003     DOI: 10.1007/pl00000586

Source DB:  PubMed          Journal:  Cell Mol Life Sci        ISSN: 1420-682X            Impact factor:   9.261


  10 in total

1.  Viper venom-induced oxidative stress and activation of inflammatory cytokines: a therapeutic approach for overlooked issues of snakebite management.

Authors:  M Sebastin Santhosh; M Shanmuga Sundaram; K Sunitha; K Kemparaju; K S Girish
Journal:  Inflamm Res       Date:  2013-05-09       Impact factor: 4.575

2.  Protein kinase C-δ isoform mediates lysosome labilization in DNA damage-induced apoptosis.

Authors:  Nicolas Parent; Max Scherer; Gerhard Liebisch; Gerd Schmitz; Richard Bertrand
Journal:  Int J Oncol       Date:  2010-12-20       Impact factor: 5.650

3.  Low concentration of a dioxin (2, 3, 7, 8 TCDD) affects the glycosidases and Acid phosphatase activity in mice hepatocytes.

Authors:  Jyoti Jigyasi; Rahul Kundu
Journal:  Dose Response       Date:  2014-07-30       Impact factor: 2.658

4.  Foreign body-type multinucleated giant cell formation is potently induced by alpha-tocopherol and prevented by the diacylglycerol kinase inhibitor R59022.

Authors:  Amy K McNally; James M Anderson
Journal:  Am J Pathol       Date:  2003-09       Impact factor: 4.307

5.  Phospholipase A2 isolated from the venom of Crotalus durissus terrificus inactivates dengue virus and other enveloped viruses by disrupting the viral envelope.

Authors:  Vanessa Danielle Muller; Ricardo Oliveira Soares; Nilton Nascimento dos Santos; Amanda Cristina Trabuco; Adelia Cristina Cintra; Luiz Tadeu Figueiredo; Antonio Caliri; Suely Vilela Sampaio; Victor Hugo Aquino
Journal:  PLoS One       Date:  2014-11-10       Impact factor: 3.240

Review 6.  Regulation of apoptosis-associated lysosomal membrane permeabilization.

Authors:  Ann-Charlotte Johansson; Hanna Appelqvist; Cathrine Nilsson; Katarina Kågedal; Karin Roberg; Karin Ollinger
Journal:  Apoptosis       Date:  2010-05       Impact factor: 4.677

Review 7.  Pathogenesis and Management of COVID-19.

Authors:  Khalid O Alfarouk; Sari T S AlHoufie; Samrein B M Ahmed; Mona Shabana; Ahmed Ahmed; Saad S Alqahtani; Ali S Alqahtani; Ali M Alqahtani; AbdelRahman M Ramadan; Mohamed E Ahmed; Heyam S Ali; Adil Bashir; Jesus Devesa; Rosa A Cardone; Muntaser E Ibrahim; Laurent Schwartz; Stephan J Reshkin
Journal:  J Xenobiot       Date:  2021-05-21

8.  Cytosolic peroxidases protect the lysosome of bloodstream African trypanosomes from iron-mediated membrane damage.

Authors:  Corinna Hiller; Amrei Nissen; Diego Benítez; Marcelo A Comini; R Luise Krauth-Siegel
Journal:  PLoS Pathog       Date:  2014-04-10       Impact factor: 6.823

9.  RNA-Seq Analysis for Assessing the Early Response to DSP Toxins in Mytilus galloprovincialis Digestive Gland and Gill.

Authors:  María Verónica Prego-Faraldo; Luisa Martínez; Josefina Méndez
Journal:  Toxins (Basel)       Date:  2018-10-16       Impact factor: 4.546

10.  The allosteric activation mechanism of a phospholipase A2-like toxin from Bothrops jararacussu venom: a dynamic description.

Authors:  Antoniel A S Gomes; Fabio F Cardoso; Maximilia F Souza; Cristiano L P Oliveira; David Perahia; Angelo J Magro; Marcos R M Fontes
Journal:  Sci Rep       Date:  2020-10-01       Impact factor: 4.379

  10 in total

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