OBJECTIVE: The objective of this study was to determine if there were any differences in the parotid saliva output and composition related to caries activity. STUDY DESIGN: Stimulated parotid saliva samples were collected from 85 healthy young adults, caries-active or caries-free. Flow rates were determined, and samples were analyzed for pH and buffer capacity, total protein, electrolytes, proteins with a high performance liquid chromatography method, and histatins. RESULTS: There were no differences in flow rates or pH, but buffer capacity was higher in women than in men, and K+ and Cl- were both slightly higher in the caries-active group. The women had a significantly higher total protein concentration, as well as higher concentrations of each of the individual protein components assayed. There were no differences attributable to caries activity. CONCLUSIONS: Significant sex differences in salivary protein concentrations exist. Caries activity may be related to some salivary electrolyte alterations, but not to protein composition.
OBJECTIVE: The objective of this study was to determine if there were any differences in the parotid saliva output and composition related to caries activity. STUDY DESIGN: Stimulated parotid saliva samples were collected from 85 healthy young adults, caries-active or caries-free. Flow rates were determined, and samples were analyzed for pH and buffer capacity, total protein, electrolytes, proteins with a high performance liquid chromatography method, and histatins. RESULTS: There were no differences in flow rates or pH, but buffer capacity was higher in women than in men, and K+ and Cl- were both slightly higher in the caries-active group. The women had a significantly higher total protein concentration, as well as higher concentrations of each of the individual protein components assayed. There were no differences attributable to caries activity. CONCLUSIONS: Significant sex differences in salivary protein concentrations exist. Caries activity may be related to some salivary electrolyte alterations, but not to protein composition.
Authors: Galina Laputková; Vladimíra Schwartzová; Juraj Bánovčin; Michal Alexovič; Ján Sabo Journal: Open Life Sci Date: 2018-05-18 Impact factor: 0.938