Literature DB >> 9116683

Gene activation pathways of nerve growth factor signaling: a minireview.

J Szeberényi1.   

Abstract

PC12 rat pheochromocytoma cells provide an excellent model system to study the mechanism of nerve growth factor-induced neuronal differentiation. PC12 cells expressing a dominant inhibitory Ras protein are being used to elucidate the role of this key signal transduction protein in gene activation events accompanying morphological differentiation of these cells. The possible involvement of Ras-dependent protein phosphorylation cascades in NGF-induced gene expression are discussed in this paper.

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Year:  1996        PMID： 9116683

Source DB:  PubMed          Journal:  Neurobiology (Bp)        ISSN： 1216-8068


  7 in total

1.  Ovarian hormones elicit phosphorylation of Akt and extracellular-signal regulated kinase in explants of the cerebral cortex.

Authors:  M Singh
Journal:  Endocrine       Date:  2001-04       Impact factor: 3.633

2.  Colostrinin-driven neurite outgrowth requires p53 activation in PC12 cells.

Authors:  Attila Bacsi; G John Stanton; Thomas K Hughes; Marian Kruze; Istvan Boldogh
Journal:  Cell Mol Neurobiol       Date:  2005-11       Impact factor: 5.046

3.  Development of an ischemic tolerance model in a PC12 cell line.

Authors:  Joëlle A Hillion; Kenzo Takahashi; Dragan Maric; Christl Ruetzler; Jeffery L Barker; John M Hallenbeck
Journal:  J Cereb Blood Flow Metab       Date:  2005-02       Impact factor: 6.200

4.  The growth-inhibitory Ndrg1 gene is a Myc negative target in human neuroblastomas and other cell types with overexpressed N- or c-myc.

Authors:  Jun Li; Leo Kretzner
Journal:  Mol Cell Biochem       Date:  2003-08       Impact factor: 3.396

5.  Divergent impact of progesterone and medroxyprogesterone acetate (Provera) on nuclear mitogen-activated protein kinase signaling.

Authors:  Jon Nilsen; Roberta Diaz Brinton
Journal:  Proc Natl Acad Sci U S A       Date:  2003-08-18       Impact factor: 11.205

6.  Protein phosphatase magnesium dependent 1A (PPM1A) plays a role in the differentiation and survival processes of nerve cells.

Authors:  Meytal Shohat; Daniella Ben-Meir; Sara Lavi
Journal:  PLoS One       Date:  2012-02-27       Impact factor: 3.240

7.  The transcriptional corepressor NAB2 inhibits NGF-induced differentiation of PC12 cells.

Authors:  Z Qu; L A Wolfraim; J Svaren; M U Ehrengruber; N Davidson; J Milbrandt
Journal:  J Cell Biol       Date:  1998-08-24       Impact factor: 10.539
  7 in total

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