Literature DB >> 9115388

Signal transduction: clamping down on Src activity.

B J Mayer1.   

Abstract

Recent high-resolution structures of members of the Src family of protein-tyrosine kinases illustrate how a series of cooperative intramolecular interactions represses the catalytic activity of these kinases, but allows for their rapid activation by a variety of regulatory inputs.

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Year:  1997        PMID: 9115388     DOI: 10.1016/s0960-9822(06)00141-2

Source DB:  PubMed          Journal:  Curr Biol        ISSN: 0960-9822            Impact factor:   10.834


  17 in total

1.  A logical analysis of T cell activation and anergy.

Authors:  M Kaufman; F Andris; O Leo
Journal:  Proc Natl Acad Sci U S A       Date:  1999-03-30       Impact factor: 11.205

2.  Tyrosine phosphorylation controls nuclear export of Fyn, allowing Nrf2 activation of cytoprotective gene expression.

Authors:  James W Kaspar; Anil K Jaiswal
Journal:  FASEB J       Date:  2010-11-19       Impact factor: 5.191

3.  RACK1, a receptor for activated C kinase and a homolog of the beta subunit of G proteins, inhibits activity of src tyrosine kinases and growth of NIH 3T3 cells.

Authors:  B Y Chang; K B Conroy; E M Machleder; C A Cartwright
Journal:  Mol Cell Biol       Date:  1998-06       Impact factor: 4.272

4.  Interaction between PAK and nck: a template for Nck targets and role of PAK autophosphorylation.

Authors:  Z S Zhao; E Manser; L Lim
Journal:  Mol Cell Biol       Date:  2000-06       Impact factor: 4.272

5.  The role of the linker between the SH2 domain and catalytic domain in the regulation and function of Src.

Authors:  S Gonfloni; J C Williams; K Hattula; A Weijland; R K Wierenga; G Superti-Furga
Journal:  EMBO J       Date:  1997-12-15       Impact factor: 11.598

6.  The pool of preactivated Lck in the initiation of T-cell signaling: a critical re-evaluation of the Lck standby model.

Authors:  Ondřej Ballek; Jan Valečka; Jasper Manning; Dominik Filipp
Journal:  Immunol Cell Biol       Date:  2014-11-25       Impact factor: 5.126

7.  Regulation of c-SRC activity and function by the adapter protein CAS.

Authors:  M R Burnham; P J Bruce-Staskal; M T Harte; C L Weidow; A Ma; S A Weed; A H Bouton
Journal:  Mol Cell Biol       Date:  2000-08       Impact factor: 4.272

8.  Lck-dependent Fyn activation requires C terminus-dependent targeting of kinase-active Lck to lipid rafts.

Authors:  Dominik Filipp; Behrouz Moemeni; Alessandra Ferzoco; Kirishanthy Kathirkamathamby; Jenny Zhang; Ondrej Ballek; Dominique Davidson; André Veillette; Michael Julius
Journal:  J Biol Chem       Date:  2008-07-27       Impact factor: 5.157

9.  Leukocyte antigen-related protein tyrosine phosphatase negatively regulates hydrogen peroxide-induced vascular smooth muscle cell apoptosis.

Authors:  Juxiang Li; Xi-Lin Niu; Nageswara R Madamanchi
Journal:  J Biol Chem       Date:  2008-10-14       Impact factor: 5.157

10.  Maturation of the tyrosine kinase c-src as a kinase and as a substrate depends on the molecular chaperone Hsp90.

Authors:  Y Xu; M A Singer; S Lindquist
Journal:  Proc Natl Acad Sci U S A       Date:  1999-01-05       Impact factor: 11.205

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