Literature DB >> 9115386

Apoptosis: Bcl-2-related proteins get connected.

M D Jacobson1.   

Abstract

Bcl-2 family proteins are key intracellular regulators of programmed cell death. Several recent discoveries demonstrate how these proteins interact with the molecular machinery that controls and executes the cell-death programme, and how they can themselves be regulated by extracellular survival signals.

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Substances:

Year:  1997        PMID: 9115386     DOI: 10.1016/s0960-9822(06)00136-9

Source DB:  PubMed          Journal:  Curr Biol        ISSN: 0960-9822            Impact factor:   10.834


  18 in total

1.  Bax oligomerization is required for channel-forming activity in liposomes and to trigger cytochrome c release from mitochondria.

Authors:  B Antonsson; S Montessuit; S Lauper; R Eskes; J C Martinou
Journal:  Biochem J       Date:  2000-01-15       Impact factor: 3.857

2.  Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane.

Authors:  R Eskes; S Desagher; B Antonsson; J C Martinou
Journal:  Mol Cell Biol       Date:  2000-02       Impact factor: 4.272

Review 3.  Histopathological evaluation of apoptosis in cancer.

Authors:  Y Soini; P Pääkkö; V P Lehto
Journal:  Am J Pathol       Date:  1998-10       Impact factor: 4.307

4.  Bim: a novel member of the Bcl-2 family that promotes apoptosis.

Authors:  L O'Connor; A Strasser; L A O'Reilly; G Hausmann; J M Adams; S Cory; D C Huang
Journal:  EMBO J       Date:  1998-01-15       Impact factor: 11.598

5.  The experimental and clinical study on the effect of curcumin on cell cycle proteins and regulating proteins of apoptosis in acute myelogenous leukemia.

Authors:  Yan Chen; Yudan Wu; Jing He; Wenjuan Chen
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2002

6.  Transgenic mice expressing human Bcl-2 in their neurons are resistant to 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine neurotoxicity.

Authors:  D Offen; P M Beart; N S Cheung; C J Pascoe; A Hochman; S Gorodin; E Melamed; R Bernard; O Bernard
Journal:  Proc Natl Acad Sci U S A       Date:  1998-05-12       Impact factor: 11.205

7.  Regional selective neuronal degeneration after protein phosphatase inhibition in hippocampal slice cultures: evidence for a MAP kinase-dependent mechanism.

Authors:  E Rundén; P O Seglen; F M Haug; O P Ottersen; T Wieloch; M Shamloo; J H Laake
Journal:  J Neurosci       Date:  1998-09-15       Impact factor: 6.167

8.  Protein phosphatase 1alpha is a Ras-activated Bad phosphatase that regulates interleukin-2 deprivation-induced apoptosis.

Authors:  V Ayllón; C Martínez-A; A García; X Cayla; A Rebollo
Journal:  EMBO J       Date:  2000-05-15       Impact factor: 11.598

9.  Depletion of Bcl-2 by an antisense oligonucleotide induces apoptosis accompanied by oxidation and externalization of phosphatidylserine in NCI-H226 lung carcinoma cells.

Authors:  Patrick P Koty; Yulia Y Tyurina; Vladimir A Tyurin; Shang-Xi Li; Valerian E Kagan
Journal:  Mol Cell Biochem       Date:  2002 May-Jun       Impact factor: 3.396

10.  Dissociation of cytokine-induced phosphorylation of Bad and activation of PKB/akt: involvement of MEK upstream of Bad phosphorylation.

Authors:  M P Scheid; V Duronio
Journal:  Proc Natl Acad Sci U S A       Date:  1998-06-23       Impact factor: 11.205

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