| Literature DB >> 911403 |
Abstract
Metopyrone, an inhibitor of glucocorticoid synthesis, blocks the development of susceptibility to audiogenic seizures in C57BL/6Bg mice after either acoustic priming at 19 days of age or ethanol withdrawal at 70-80 days of age, whereas it has no effect on the development of genetic susceptibility in DBA/1Bg mice. This suggests that there may be similar developmental mechanisms for effects of acoustic priming and ethanol withdrawal on audiogenic seizure risk, which may be different from that for the genetic susceptibility of DBA/1Bg mice.Entities:
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Year: 1977 PMID： 911403 DOI： 10.1007/bf01066802
Source DB: PubMed Journal: Behav Genet ISSN： 0001-8244 Impact factor: 2.805