Literature DB >> 911352

Experimental radiation synovectomy by 165Dy ferric hydroxide macroaggregate.

C B Sledge, J Noble, D J Hnatowich, R Kramer, S Shortkroff.   

Abstract

The short half-life beta emitter 165Dy coprecipitated as a macroaggregate with ferric hydroxide (FHMA) has been shown to destroy knee synovium in the antigen-induced arthritic rabbit. Using 153Gd as a gamma tracer for leakage studies revealed that the leakage of this system from rabbit knee joints never exceeded 1.2% over 24 hours. This is such less than the leakage rates reported from any human studies or our rabbit studies using 198Au.

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Year:  1977        PMID: 911352     DOI: 10.1002/art.1780200706

Source DB:  PubMed          Journal:  Arthritis Rheum        ISSN: 0004-3591


  5 in total

1.  A tissue-culture model of cartilage breakdown in rheumatoid arthritis. Quantitative aspects of proteoglycan release.

Authors:  J Steinberg; C B Sledge; J Noble; C R Stirrat
Journal:  Biochem J       Date:  1979-05-15       Impact factor: 3.857

2.  Beta-particle dosimetry in radiation synovectomy.

Authors:  L S Johnson; J C Yanch; S Shortkroff; C L Barnes; A I Spitzer; C B Sledge
Journal:  Eur J Nucl Med       Date:  1995-09

3.  Influence of x-ray treatment on antigen-induced experimental arthritis.

Authors:  C Steffen; C Müller; K Stellamor; J Zeitlhofer
Journal:  Ann Rheum Dis       Date:  1982-10       Impact factor: 19.103

4.  MR evaluation of radiation synovectomy of the knee by means of intra-articular injection of holmium-166-chitosan complex in patients with rheumatoid arthritis: results at 4-month follow-up.

Authors:  Sang Hoon Lee; Jin Suck Suh; Ho Seok Kim; Jong Doo Lee; Jungsik Song; Soo Kon Lee
Journal:  Korean J Radiol       Date:  2003 Jul-Sep       Impact factor: 3.500

Review 5.  The various therapeutic applications of the medical isotope holmium-166: a narrative review.

Authors:  Nienke J M Klaassen; Mark J Arntz; Alexandra Gil Arranja; Joey Roosen; J Frank W Nijsen
Journal:  EJNMMI Radiopharm Chem       Date:  2019-08-05
  5 in total

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