Literature DB >> 9112762

Study of the interaction between novel ruthenium(II)-polypyridyl complexes and calf thymus DNA.

G Yang1, J Z Wu, L Wang, L N Ji, X Tian.   

Abstract

Four new complexes L2RuL'2+, where L = 2,2'-bipyridine (bpy) and 1,10-phenanthroline (phen), L' are Schiff bases or phenylhydrazones derived from 4,5-diazafluoren-9-one (AFO), were prepared. They were characterized by elemental analyses, absorption, IR, and emission spectra. The binding of these complexes to calf thymus DNA has been investigated by absorption, circular dichroism spectroscopy, and viscosity measurement. The experimental results show that the complexes bind to calf thymus DNA by three kinds of binding modes, respectively-electrostatic mode, nonintercalative binding mode, and intercalative binding mode.

Entities:  

Mesh:

Substances:

Year:  1997        PMID: 9112762     DOI: 10.1016/s0162-0134(96)00194-8

Source DB:  PubMed          Journal:  J Inorg Biochem        ISSN: 0162-0134            Impact factor:   4.155


  3 in total

1.  Biophysical studies of a ruthenium(II) polypyridyl complex binding to DNA and RNA prove that nucleic acid structure has significant effects on binding behaviors.

Authors:  Hong Xu; Yi Liang; Peng Zhang; Fen Du; Bing-Rui Zhou; Jun Wu; Jian-Hong Liu; Zhi-Gang Liu; Liang-Nian Ji
Journal:  J Biol Inorg Chem       Date:  2005-09-23       Impact factor: 3.358

2.  Synthesis, characterization, and DNA binding of a novel ligand and its Cu (II) complex.

Authors:  Mei-Jin Li; Tao-Yu Lan; Zhi-Shan Lin; Changqing Yi; Guo-Nan Chen
Journal:  J Biol Inorg Chem       Date:  2013-12       Impact factor: 3.358

3.  Tris(1,10-phenanthroline-κ(2) N,N')ruthenium(II) bis-(perchlorate).

Authors:  Mariana Kozlowska; Pawel Rodziewicz; Diana Malgorzata Brus; Justyna Czyrko; Krzysztof Brzezinski
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2012-11-30
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.